Construction of luciferase-expressing Neospora caninum and drug screening

Construction of luciferase-expressing Neospora caninum and drug screening

Abstract Background Neospora caninum is an apicomplexan parasite that is particularly responsible for abortions in cattle and neuromuscular disease in dogs. Due to the limited effectiveness of currently available drugs, there is an urgent need for new therapeutic approaches to control neosporosis. L...

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Bibliographic Details
Main Authors: Fei Wang, Yangfei Xue, Yanqun Pei, Meng Yin, Zhepeng Sun, Zihui Zhou, Jing Liu, Qun Liu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Parasites & Vectors
Subjects:
Neospora caninum
Firefly luciferase
CRISPR/Cas9
TAK-632
Inhibition
Online Access:https://doi.org/10.1186/s13071-024-06195-8

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