<i>PPM1D</i> Is a Therapeutic Target in Childhood Neural Tumors

<i>PPM1D</i> Is a Therapeutic Target in Childhood Neural Tumors

Childhood medulloblastoma and high-risk neuroblastoma frequently present with segmental gain of chromosome 17q corresponding to aggressive tumors and poor patient prognosis. Located within the 17q-gained chromosomal segments is <i>PPM1D</i> at chromosome 17q23.2. <i>PPM1D</i>...

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Bibliographic Details
Main Authors: Jelena Milosevic, Diana Treis, Susanne Fransson, Gabriel Gallo-Oller, Baldur Sveinbjörnsson, Nina Eissler, Keiji Tanino, Kazuyasu Sakaguchi, Tommy Martinsson, Malin Wickström, Per Kogner, John Inge Johnsen
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cancers
Subjects:
neuroblastoma
medulloblastoma
chromosome 17q gain
p53
WIP1
<i>PPM1D</i>
Online Access:https://www.mdpi.com/2072-6694/13/23/6042

Internet

https://www.mdpi.com/2072-6694/13/23/6042

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