Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis
We report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vasc...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2010-09-01
|
| Series: | Rare Tumors |
| Online Access: | https://doi.org/10.4081/rt.2010.e46 |
| _version_ | 1818260768889503744 |
|---|---|
| author | Lalitha M Sitaraman John G Linn Kristina A Matkowskyj Jeffrey D Wayne |
| author_facet | Lalitha M Sitaraman John G Linn Kristina A Matkowskyj Jeffrey D Wayne |
| author_sort | Lalitha M Sitaraman |
| collection | DOAJ |
| description | We report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vascular splenic lesions or a metastatic focus of a prior sarcoma. The patient was treated with splenectomy, which has proved both diagnostic and therapeutic in this and other cases of SANT. Although histology can lead to the diagnosis of vascular tumor, immunohistochemistry is the only way to confirm the diagnosis of SANT. The etiology of SANT is unknown. SANT of the spleen is a benign lesion that does not recur after splenectomy. |
| first_indexed | 2024-12-12T18:36:35Z |
| format | Article |
| id | doaj.art-60193c8e2ba643468f3e8a464c595f33 |
| institution | Directory Open Access Journal |
| issn | 2036-3613 |
| language | English |
| last_indexed | 2024-12-12T18:36:35Z |
| publishDate | 2010-09-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Rare Tumors |
| spelling | doaj.art-60193c8e2ba643468f3e8a464c595f332022-12-22T00:15:45ZengSAGE PublishingRare Tumors2036-36132010-09-01210.4081/rt.2010.e46Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasisLalitha M Sitaraman0John G Linn1Kristina A Matkowskyj2Jeffrey D Wayne3Feinberg School of Medicine; Northwestern University, Chicago, USADepartment of Surgery; Northwestern University, Chicago, USADepartment of Pathology, Northwestern University, Chicago, USADepartment of Surgery; Northwestern University, Chicago, USAWe report a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen presenting as an incidental splenic mass in a patient with a history of retroperitoneal spindle cell sarcoma. Imaging studies and preoperative fine needle biopsy failed to differentiate this lesion from other vascular splenic lesions or a metastatic focus of a prior sarcoma. The patient was treated with splenectomy, which has proved both diagnostic and therapeutic in this and other cases of SANT. Although histology can lead to the diagnosis of vascular tumor, immunohistochemistry is the only way to confirm the diagnosis of SANT. The etiology of SANT is unknown. SANT of the spleen is a benign lesion that does not recur after splenectomy.https://doi.org/10.4081/rt.2010.e46 |
| spellingShingle | Lalitha M Sitaraman John G Linn Kristina A Matkowskyj Jeffrey D Wayne Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis Rare Tumors |
| title | Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
| title_full | Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
| title_fullStr | Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
| title_full_unstemmed | Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
| title_short | Sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
| title_sort | sclerosing angiomatoid nodular transformation of the spleen masquerading as a sarcoma metastasis |
| url | https://doi.org/10.4081/rt.2010.e46 |
| work_keys_str_mv | AT lalithamsitaraman sclerosingangiomatoidnodulartransformationofthespleenmasqueradingasasarcomametastasis AT johnglinn sclerosingangiomatoidnodulartransformationofthespleenmasqueradingasasarcomametastasis AT kristinaamatkowskyj sclerosingangiomatoidnodulartransformationofthespleenmasqueradingasasarcomametastasis AT jeffreydwayne sclerosingangiomatoidnodulartransformationofthespleenmasqueradingasasarcomametastasis |