Rapid and highly-specific generation of targeted DNA sequencing libraries enabled by linking capture probes with universal primers.
Targeted Next Generation Sequencing (NGS) is being adopted increasingly broadly in many research, commercial and clinical settings. Currently used target capture methods, however, typically require complex and lengthy (sometimes multi-day) workflows that complicates their use in certain applications...
Main Authors: | Joel Pel, Amy Leung, Wendy W Y Choi, Milenko Despotovic, W Lloyd Ung, Gosuke Shibahara, Laura Gelinas, Andre Marziali |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0208283 |
Similar Items
-
Duplex Proximity Sequencing (Pro-Seq): A method to improve DNA sequencing accuracy without the cost of molecular barcoding redundancy.
by: Joel Pel, et al.
Published: (2018-01-01) -
Winnowing DNA for rare sequences: highly specific sequence and methylation based enrichment.
by: Jason D Thompson, et al.
Published: (2012-01-01) -
The bacterial hitchhiker’s guide to COI: Universal primer-based COI capture probes fail to exclude bacterial DNA, but 16S capture leaves metazoa behind
by: Sanni Hintikka, et al.
Published: (2022-05-01) -
Graphs in Libraries: A Primer
by: James E. Powell, et al.
Published: (2011-12-01) -
Multifunctional Nanotechnology-Enabled Sensors for Rapid Capture and Detection of Pathogens
by: Fatima Mustafa, et al.
Published: (2017-09-01)