Cathepsin V regulates cell cycle progression and histone stability in the nucleus of breast cancer cells

Cathepsin V regulates cell cycle progression and histone stability in the nucleus of breast cancer cells

Introduction: We previously identified that Cathepsin V (CTSV) expression is associated with poor prognosis in ER+ breast cancer, particularly within the Luminal A subtype. Examination of the molecular role of the protease within Luminal A tumours, revealed that CTSV promotes tumour cell invasion an...

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Bibliographic Details
Main Authors: Naphannop Sereesongsaeng, James F. Burrows, Christopher J. Scott, Klaudia Brix, Roberta E. Burden
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
cysteine cathepsin
protease
histone
chaperone
nucleus
importin
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1271435/full

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