Complex GABAB receptor complexes: how to generate multiple functionally distinct units from a single receptor

Complex GABAB receptor complexes: how to generate multiple functionally distinct units from a single receptor

The main inhibitory neurotransmitter, GABA, acts on both ligand-gated and G protein-coupled receptors, the GABAA/C and GABAB receptors, respectively. The later play important roles in modulating many synapses, both at the pre- and post-synaptic levels, and are then still considered as interesting ta...

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Bibliographic Details
Main Authors: Chanjuan eXU, Wenhua eZhang, Philippe eRondard, Jean-philippe ePin, Jianfeng eLiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Pharmacology
Subjects:
Signal Transduction
dimers
GABAB receptor
large oligomers
G-protein coupled receptor interacting proteins
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00012/full

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