FGF18 signaling in the hair cycle resting phase determines radioresistance of hair follicles by arresting hair cycling

FGF18 signaling in the hair cycle resting phase determines radioresistance of hair follicles by arresting hair cycling

Purpose: Telogen (resting phase) hair follicles (HFs) are more radioresistant than their anagen (growth phase) counterparts. Fibroblast growth factor (FGF) 18 is strongly expressed in telogen HFs to maintain the telogen phase, whereas several other FGFs exert radioprotective effects; however, the ro...

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Main Authors: Mitsuko Kawano, PhD, Sachiko Umeda, BS, Takeshi Yasuda, PhD, Mayumi Fujita, PhD, Atsuko Ishikawa, BS, Toru Imamura, PhD, Takashi Imai, PhD, Fumiaki Nakayama, MD, PhD
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109416300276

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