The spatiotemporal heterogeneity of the biophysical microenvironment during hematopoietic stem cell development: from embryo to adult

The spatiotemporal heterogeneity of the biophysical microenvironment during hematopoietic stem cell development: from embryo to adult

Abstract Hematopoietic stem cells (HSCs) with the ability to self-renew and differentiate are responsible for maintaining the supply of all types of blood cells. The complex and delicate microenvironment surrounding HSCs is called the HSC niche and can provide physical, chemical, and biological stim...

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Bibliographic Details
Main Authors: Guolin Shi, Pan Zhang, Xi Zhang, Jing Li, Xinmin Zheng, Jinxiao Yan, Nu Zhang, Hui Yang
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Stem Cell Research & Therapy
Subjects:
Spatiotemporal heterogeneity
Biophysical microenvironment
Hematopoietic stem cells
Fate regulation
Online Access:https://doi.org/10.1186/s13287-023-03464-8

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