Rapid binding to protofilament edge sites facilitates tip tracking of EB1 at growing microtubule plus-ends

Rapid binding to protofilament edge sites facilitates tip tracking of EB1 at growing microtubule plus-ends

EB1 is a key cellular protein that delivers regulatory molecules throughout the cell via the tip-tracking of growing microtubule plus-ends. Thus, it is important to understand the mechanism for how EB1 efficiently tracks growing microtubule plus-ends. It is widely accepted that EB1 binds with higher...

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Bibliographic Details
Main Authors: Samuel J Gonzalez, Julia M Heckel, Rebecca R Goldblum, Taylor A Reid, Mark McClellan, Melissa K Gardner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-02-01
Series:eLife
Subjects:
microtubule
EB1
modeling
tubulin
protofilament
diffusion
Online Access:https://elifesciences.org/articles/91719

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