2-Butyl-6-phenyl-4,5-dihydropyridazin-3(2<em>H</em>)-one: Synthesis, In Silico Studies and In Vitro Cyclooxygenase-2 Inhibitory Activity
Pyridazinone derivatives are a great template for developing cyclooxygenase-2 (COX-2) inhibitors. The 2-butyl-6-phenyl-4,5-dihydropyridazin-3(2<i>H</i>)-one was prepared by reacting 6-phenyl-4,5-dihydropyridazin-3(2<i>H</i>)-one with <i>n</i>-butyl bromide in the...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-08-01
|
| Series: | Molbank |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-8599/2020/3/M1155 |