Distal bronchial tubes damage in patients with rheumatoid arthritis

Objective. To study prevalence and clinical picture of distal parts of bronchial tree(bronchiolitis) in pts with rheumatoid arthritis (RA). Material and methods. 104 nonsmoking pts with RA and 100 pts without RA and chronic diseases of respiratory apparatus were included. General clinical examinatio...

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Main Authors: M V Sheyanov, S K Ternovoq, E V Fominych, I N Zavrazina, V I Makolkin, V A Sulimov
Format: Article
Language:Russian
Published: IMA PRESS LLC 2009-12-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/806
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author M V Sheyanov
S K Ternovoq
E V Fominych
I N Zavrazina
V I Makolkin
V A Sulimov
author_facet M V Sheyanov
S K Ternovoq
E V Fominych
I N Zavrazina
V I Makolkin
V A Sulimov
author_sort M V Sheyanov
collection DOAJ
description Objective. To study prevalence and clinical picture of distal parts of bronchial tree(bronchiolitis) in pts with rheumatoid arthritis (RA). Material and methods. 104 nonsmoking pts with RA and 100 pts without RA and chronic diseases of respiratory apparatus were included. General clinical examination, spirometry, bodyplethysmography, examination of lung diffusion capacity (LDC) and multispiralcomputed tomography (MSCT) of lungs were performed. Results. Direct and indirect bronchiolitis signs were revealed with MSCT in 36 (35%) ptswith RA and 1 pt of control group (p<0,01). Pts with signs of bronchiolitis complained of shortness of breath (69% of pts), cough (56%), phlegm discharge (56%), heavy breathing (25%). Obstructive lung ventilation disturbances were revealed in 19 (53%) RA pts with bronchiolitis. Restrictive disturbances and LDC decrease were present in 3 (8%) pts. High frequency of oligosymptomatic bronchiolitis course was found in RA pts. Bronchiolitis symptoms in RA pts coincided with signs of proximal bronchial tubes damage forming picture of diffuse damage of bronchial tree. Conclusion. Bronchiolitis is a prevalent variant of respiratory apparatus damage in pts with RA. Pts with MSCT signs of bronchiolitis often have cough, phlegm discharge, shortness of breath, heavy breathing. Lung ventilation disturbances of obstructive type are common but part of pts has normal lung functional measures or restriction. Oligosymptomatic forms of distal bronchial tubes damage are prevalent in RA pts. Lung MSCT is the main method of bronchiolitis diagnostics because bronchiolitis induces nonspecific clinical signs and RA pts have multilevel respiratory apparatus damage. MSCT reveals signs of distal bronchial tubes damage in 35% of RA pts.
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spelling doaj.art-6037ee9408d048fd81c9e46b900e44282023-03-22T13:45:45ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922009-12-01476141910.14412/1995-4484-2009-669746Distal bronchial tubes damage in patients with rheumatoid arthritisM V SheyanovS K TernovoqE V FominychI N ZavrazinaV I MakolkinV A SulimovObjective. To study prevalence and clinical picture of distal parts of bronchial tree(bronchiolitis) in pts with rheumatoid arthritis (RA). Material and methods. 104 nonsmoking pts with RA and 100 pts without RA and chronic diseases of respiratory apparatus were included. General clinical examination, spirometry, bodyplethysmography, examination of lung diffusion capacity (LDC) and multispiralcomputed tomography (MSCT) of lungs were performed. Results. Direct and indirect bronchiolitis signs were revealed with MSCT in 36 (35%) ptswith RA and 1 pt of control group (p<0,01). Pts with signs of bronchiolitis complained of shortness of breath (69% of pts), cough (56%), phlegm discharge (56%), heavy breathing (25%). Obstructive lung ventilation disturbances were revealed in 19 (53%) RA pts with bronchiolitis. Restrictive disturbances and LDC decrease were present in 3 (8%) pts. High frequency of oligosymptomatic bronchiolitis course was found in RA pts. Bronchiolitis symptoms in RA pts coincided with signs of proximal bronchial tubes damage forming picture of diffuse damage of bronchial tree. Conclusion. Bronchiolitis is a prevalent variant of respiratory apparatus damage in pts with RA. Pts with MSCT signs of bronchiolitis often have cough, phlegm discharge, shortness of breath, heavy breathing. Lung ventilation disturbances of obstructive type are common but part of pts has normal lung functional measures or restriction. Oligosymptomatic forms of distal bronchial tubes damage are prevalent in RA pts. Lung MSCT is the main method of bronchiolitis diagnostics because bronchiolitis induces nonspecific clinical signs and RA pts have multilevel respiratory apparatus damage. MSCT reveals signs of distal bronchial tubes damage in 35% of RA pts.https://rsp.mediar-press.net/rsp/article/view/806rheumatoid arthritisbronchiolitisbronchial obstructionmultispiral computed tomography
spellingShingle M V Sheyanov
S K Ternovoq
E V Fominych
I N Zavrazina
V I Makolkin
V A Sulimov
Distal bronchial tubes damage in patients with rheumatoid arthritis
Научно-практическая ревматология
rheumatoid arthritis
bronchiolitis
bronchial obstruction
multispiral computed tomography
title Distal bronchial tubes damage in patients with rheumatoid arthritis
title_full Distal bronchial tubes damage in patients with rheumatoid arthritis
title_fullStr Distal bronchial tubes damage in patients with rheumatoid arthritis
title_full_unstemmed Distal bronchial tubes damage in patients with rheumatoid arthritis
title_short Distal bronchial tubes damage in patients with rheumatoid arthritis
title_sort distal bronchial tubes damage in patients with rheumatoid arthritis
topic rheumatoid arthritis
bronchiolitis
bronchial obstruction
multispiral computed tomography
url https://rsp.mediar-press.net/rsp/article/view/806
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AT inzavrazina distalbronchialtubesdamageinpatientswithrheumatoidarthritis
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