Polymyositis and the Spectrum of Scleroderma Disorders
Polymyositis (PM) is usually associated to other autoimmune or connective tissue diseases. The authors report the case of a 59-year-old man with pulmonary fibrosis, who presented with constitutional symptoms and gradually developed proximal muscle weakness, Raynaud phenomenon, and dysphagia. Besides...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SMC MEDIA SRL
2015-12-01
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| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | http://ejcrim.com/index.php/EJCRIM/article/view/346 |
| _version_ | 1818209871454011392 |
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| author | Joana Cochicho João Madaleno Emília Louro Adélia Simão Armando Carvalho |
| author_facet | Joana Cochicho João Madaleno Emília Louro Adélia Simão Armando Carvalho |
| author_sort | Joana Cochicho |
| collection | DOAJ |
| description | Polymyositis (PM) is usually associated to other autoimmune or connective tissue diseases. The authors report the case of a 59-year-old man with pulmonary fibrosis, who presented with constitutional symptoms and gradually developed proximal muscle weakness, Raynaud phenomenon, and dysphagia. Besides creatine kinase (CK) elevation, he had positive anti-Polymyositis-Scleromyositis (PM-Scl) and anti-Sjögren's-syndrome A (SSA) antibodies. Nailfold capillaroscopy showed a scleroderma pattern and muscle biopsy revealed necrosis, regeneration of muscle fibers, and inflammatory infiltrate. Prednisolone was started, with great improvement. Taking into account the overlap features between PM and systemic sclerosis sine scleroderma, it is important to closely monitor the patient for signs of pulmonary and cardiac decompensation. |
| first_indexed | 2024-12-12T05:07:36Z |
| format | Article |
| id | doaj.art-603e9ed3969b467ba3628cb821cfbebb |
| institution | Directory Open Access Journal |
| issn | 2284-2594 |
| language | English |
| last_indexed | 2024-12-12T05:07:36Z |
| publishDate | 2015-12-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj.art-603e9ed3969b467ba3628cb821cfbebb2022-12-22T00:37:04ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942015-12-013110.12890/2015_000346131Polymyositis and the Spectrum of Scleroderma DisordersJoana Cochicho0João Madaleno1Emília Louro2Adélia Simão3Armando Carvalho4Coimbra Hospital and Universitary CentreCoimbra Hospital and Universitary CentreCoimbra Hospital and Universitary CentreCoimbra Hospital and Universitary CentreCoimbra Hospital and Universitary CentrePolymyositis (PM) is usually associated to other autoimmune or connective tissue diseases. The authors report the case of a 59-year-old man with pulmonary fibrosis, who presented with constitutional symptoms and gradually developed proximal muscle weakness, Raynaud phenomenon, and dysphagia. Besides creatine kinase (CK) elevation, he had positive anti-Polymyositis-Scleromyositis (PM-Scl) and anti-Sjögren's-syndrome A (SSA) antibodies. Nailfold capillaroscopy showed a scleroderma pattern and muscle biopsy revealed necrosis, regeneration of muscle fibers, and inflammatory infiltrate. Prednisolone was started, with great improvement. Taking into account the overlap features between PM and systemic sclerosis sine scleroderma, it is important to closely monitor the patient for signs of pulmonary and cardiac decompensation.http://ejcrim.com/index.php/EJCRIM/article/view/346Polymyositis, Systemic sclerosis sine scleroderma, Overlap syndrome |
| spellingShingle | Joana Cochicho João Madaleno Emília Louro Adélia Simão Armando Carvalho Polymyositis and the Spectrum of Scleroderma Disorders European Journal of Case Reports in Internal Medicine Polymyositis, Systemic sclerosis sine scleroderma, Overlap syndrome |
| title | Polymyositis and the Spectrum of Scleroderma Disorders |
| title_full | Polymyositis and the Spectrum of Scleroderma Disorders |
| title_fullStr | Polymyositis and the Spectrum of Scleroderma Disorders |
| title_full_unstemmed | Polymyositis and the Spectrum of Scleroderma Disorders |
| title_short | Polymyositis and the Spectrum of Scleroderma Disorders |
| title_sort | polymyositis and the spectrum of scleroderma disorders |
| topic | Polymyositis, Systemic sclerosis sine scleroderma, Overlap syndrome |
| url | http://ejcrim.com/index.php/EJCRIM/article/view/346 |
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