High-throughput optical sensing of peri-cellular oxygen in cardiac cells: system characterization, calibration, and testing
Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) represent a scalable experimental model relevant to human physiology. Oxygen consumption of hiPSC-CMs has not been studied in high-throughput (HT) format plates used in pre-clinical studies. Here, we provide comprehensive charact...
Main Authors: | Weizhen Li, David McLeod, John T. Ketzenberger, Grant Kowalik, Rebekah Russo, Zhenyu Li, Matthew W. Kay, Emilia Entcheva |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-06-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1214493/full |
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