Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study
Background: Post-traumatic stress disorder (PTSD) is the most common psychiatric sequelae among novel coronavirus disease (COVID-19) patients. The aim of this study was to determine the prevalence of PTSD symptoms, PTSD-related factors, and its relationship with quality of life at long-term follow-u...
| Main Authors: | , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-01-01
|
| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2021.782478/full |
| _version_ | 1819228653598277632 |
|---|---|
| author | Liqun Huang Xiaohua Xu Lingjie Zhang Danwen Zheng Yuntao Liu Bing Feng Jiajun Hu Qiaoli Lin Xiaotu Xi Qian Wang Meixuan Lin Xin Zhou Zehui He Heng Weng Qiuying Deng Banghan Ding Jianwen Guo Zhongde Zhang Zhongde Zhang |
| author_facet | Liqun Huang Xiaohua Xu Lingjie Zhang Danwen Zheng Yuntao Liu Bing Feng Jiajun Hu Qiaoli Lin Xiaotu Xi Qian Wang Meixuan Lin Xin Zhou Zehui He Heng Weng Qiuying Deng Banghan Ding Jianwen Guo Zhongde Zhang Zhongde Zhang |
| author_sort | Liqun Huang |
| collection | DOAJ |
| description | Background: Post-traumatic stress disorder (PTSD) is the most common psychiatric sequelae among novel coronavirus disease (COVID-19) patients. The aim of this study was to determine the prevalence of PTSD symptoms, PTSD-related factors, and its relationship with quality of life at long-term follow-up in hospitalized COVID-19 survivors.Methods: A cross-sectional study was undertaken to evaluate the health consequences of hospitalized COVID-19 survivors. All participants were interviewed face-to-face through a series of questionnaires: a researcher-developed symptom questionnaire, the Post-traumatic Stress Disorder Checklist–Civilian Version, the Generalized Anxiety Disorder 7-item, and the 36-item Short Form.Results: A total of 574 participants were enrolled with an average age of 57 years. The median follow-up time post-discharge was 193.9 days (SD = 15.32). Among the participants, 77.9% of survivors presented with at least one symptom, where fatigue or muscle weakness (47.9%) was reported the most frequently, followed by chest distress (29.4%) and sleep difficulty (29.4%). The prevalence of PTSD was 11.15% [95% confidence interval (CI): 8.56, 13.73] with a cut-off score of 44. Factors such as respiratory symptoms [odds ratio (OR): 3.53; 95% CI: 1.68–7.42], anxiety (OR: 14.64; 95% CI: 7.09–30.21), and sleep difficulty (OR: 2.17; 95% CI: 1.14–4.16) were positively related to PTSD. Those COVID-19 survivors with potential PTSD had significantly lower quality of life than those without (P < 0.05).Conclusion: Our study illustrated that a significant number of COVID-19 survivors were suffering from physical or mental distress to varying degrees at 6 months post-discharge. People with PTSD were more likely to experience persistent respiratory symptoms and sleep difficulty, as well as anxiety and a decreased quality of life. Such survivors require greater attention to their mental health, particularly the PTSD symptoms at the early phase, which may play an important role in the recovery of both the physical and psychological health of COVID-19 survivors. |
| first_indexed | 2024-12-23T11:00:42Z |
| format | Article |
| id | doaj.art-60401ad996fa43988f2f1551cdd48aa7 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-12-23T11:00:42Z |
| publishDate | 2022-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-60401ad996fa43988f2f1551cdd48aa72022-12-21T17:49:39ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402022-01-011210.3389/fpsyt.2021.782478782478Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational StudyLiqun Huang0Xiaohua Xu1Lingjie Zhang2Danwen Zheng3Yuntao Liu4Bing Feng5Jiajun Hu6Qiaoli Lin7Xiaotu Xi8Qian Wang9Meixuan Lin10Xin Zhou11Zehui He12Heng Weng13Qiuying Deng14Banghan Ding15Jianwen Guo16Zhongde Zhang17Zhongde Zhang18The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, ChinaThe Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Medical Administration, Hubei Provincial Hospital of Traditional Chinese and Western Medicine, Wuhan, ChinaDepartment of Emergency, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Emergency, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Pharmacology of Traditional Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Medical Administration, Hubei Provincial Hospital of Traditional Chinese and Western Medicine, Wuhan, ChinaDepartment of Geriatrics, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Emergency, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaThe Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, ChinaThe Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, ChinaThe Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Clinical Epidemiology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Clinical Epidemiology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Emergency, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Emergency, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Medical Administration, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Emergency, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Research on Emergency in Traditional Chinese Medicine, Guangzhou, ChinaBackground: Post-traumatic stress disorder (PTSD) is the most common psychiatric sequelae among novel coronavirus disease (COVID-19) patients. The aim of this study was to determine the prevalence of PTSD symptoms, PTSD-related factors, and its relationship with quality of life at long-term follow-up in hospitalized COVID-19 survivors.Methods: A cross-sectional study was undertaken to evaluate the health consequences of hospitalized COVID-19 survivors. All participants were interviewed face-to-face through a series of questionnaires: a researcher-developed symptom questionnaire, the Post-traumatic Stress Disorder Checklist–Civilian Version, the Generalized Anxiety Disorder 7-item, and the 36-item Short Form.Results: A total of 574 participants were enrolled with an average age of 57 years. The median follow-up time post-discharge was 193.9 days (SD = 15.32). Among the participants, 77.9% of survivors presented with at least one symptom, where fatigue or muscle weakness (47.9%) was reported the most frequently, followed by chest distress (29.4%) and sleep difficulty (29.4%). The prevalence of PTSD was 11.15% [95% confidence interval (CI): 8.56, 13.73] with a cut-off score of 44. Factors such as respiratory symptoms [odds ratio (OR): 3.53; 95% CI: 1.68–7.42], anxiety (OR: 14.64; 95% CI: 7.09–30.21), and sleep difficulty (OR: 2.17; 95% CI: 1.14–4.16) were positively related to PTSD. Those COVID-19 survivors with potential PTSD had significantly lower quality of life than those without (P < 0.05).Conclusion: Our study illustrated that a significant number of COVID-19 survivors were suffering from physical or mental distress to varying degrees at 6 months post-discharge. People with PTSD were more likely to experience persistent respiratory symptoms and sleep difficulty, as well as anxiety and a decreased quality of life. Such survivors require greater attention to their mental health, particularly the PTSD symptoms at the early phase, which may play an important role in the recovery of both the physical and psychological health of COVID-19 survivors.https://www.frontiersin.org/articles/10.3389/fpsyt.2021.782478/fullCOVID-19survivorsclinical sequelaepost-traumatic stress disorderquality of life (QoL) |
| spellingShingle | Liqun Huang Xiaohua Xu Lingjie Zhang Danwen Zheng Yuntao Liu Bing Feng Jiajun Hu Qiaoli Lin Xiaotu Xi Qian Wang Meixuan Lin Xin Zhou Zehui He Heng Weng Qiuying Deng Banghan Ding Jianwen Guo Zhongde Zhang Zhongde Zhang Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study Frontiers in Psychiatry COVID-19 survivors clinical sequelae post-traumatic stress disorder quality of life (QoL) |
| title | Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study |
| title_full | Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study |
| title_fullStr | Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study |
| title_full_unstemmed | Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study |
| title_short | Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study |
| title_sort | post traumatic stress disorder symptoms and quality of life of covid 19 survivors at 6 month follow up a cross sectional observational study |
| topic | COVID-19 survivors clinical sequelae post-traumatic stress disorder quality of life (QoL) |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2021.782478/full |
| work_keys_str_mv | AT liqunhuang posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT xiaohuaxu posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT lingjiezhang posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT danwenzheng posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT yuntaoliu posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT bingfeng posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT jiajunhu posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT qiaolilin posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT xiaotuxi posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT qianwang posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT meixuanlin posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT xinzhou posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT zehuihe posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT hengweng posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT qiuyingdeng posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT banghanding posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT jianwenguo posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT zhongdezhang posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy AT zhongdezhang posttraumaticstressdisordersymptomsandqualityoflifeofcovid19survivorsat6monthfollowupacrosssectionalobservationalstudy |