Non-AUG Translation Initiation Generates Peroxisomal Isoforms of 6-Phosphogluconate Dehydrogenase in Fungi

Non-AUG Translation Initiation Generates Peroxisomal Isoforms of 6-Phosphogluconate Dehydrogenase in Fungi

Proteins destined for transport to specific organelles usually contain targeting information, which are embedded in their sequence. Many enzymes are required in more than one cellular compartment and different molecular mechanisms are used to achieve dual localization. Here we report a cryptic type...

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Bibliographic Details
Main Authors: Marco Kremp, Elena Bittner, Domenica Martorana, Alexander Klingenberger, Thorsten Stehlik, Michael Bölker, Johannes Freitag
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
dual targeting
pentose-phosphate pathway
non-AUG translation
redox-shuttle
peroxisome
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00251/full

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