Investigation on the Potential Correlation Between TP53 and Esophageal Cancer

Investigation on the Potential Correlation Between TP53 and Esophageal Cancer

Background:TP53 family members play an indispensable role in various human cancers, while the gene expression profiles, prognostic value, and potential mechanism in esophageal cancer (ESCA) are yet unclear.Methods: The expression and roles of TP53 family members in ESCA were investigated using the C...

Full description

Bibliographic Details
Main Authors:	Lihua Yao, Xiaowu Zhong, Guangcheng Huang, Qiang Ma, Lei Xu, Hong Xiao, Xiaolan Guo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-10-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	esophageal cancer expression prognosis TP53 bioinformatics
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2021.730337/full

Similar Items

TP53 Mutations in Esophageal Squamous Cell Carcinoma
by: Leqi Zhong, et al.
Published: (2023-09-01)

Expressions of TP53, PDGF and EGFR in Primary Astrocytomas and Their Correlation with Clinicopathological Features and Prognosis
by: SUN Xiaoling, et al.
Published: (2021-02-01)

Early <i>TP53</i> Alterations Shape Gastric and Esophageal Cancer Development
by: Pranshu Sahgal, et al.
Published: (2021-11-01)

Insight of Tp53 Mutations and their effect on Protein in Different Feline and Canine Neoplasms
by: Rashid Saif, et al.
Published: (2016-02-01)

The TP53 fertility network
by: Diego d'Avila Paskulin, et al.
Published: (2012-01-01)

TP53 Mutation Infers a Poor Prognosis and Is Correlated to Immunocytes Infiltration in Breast Cancer
by: Ziwen Zhang, et al.
Published: (2021-11-01)

Integrative Analysis of TP53INP2 in Head and Neck Squamous Cell Carcinoma
by: Ruoyan Cao, et al.
Published: (2021-04-01)

<i>TP53</i> in Myelodysplastic Syndromes: Recent Biological and Clinical Findings
by: Cosimo Cumbo, et al.
Published: (2020-05-01)

Identification of Novel Characteristics in TP53-Mutant Hepatocellular Carcinoma Using Bioinformatics
by: Yang Yang, et al.
Published: (2022-05-01)

Mutant TP53 G245C and R273H promote cellular malignancy in esophageal squamous cell carcinoma
by: Nan Kang, et al.
Published: (2018-08-01)

Comparative Analysis of Gene Correlation Networks of Breast Cancer Patients Based on Mutations in TP53
by: Byungkyu Park, et al.
Published: (2022-07-01)

Presence of new mutations in the TP53 gene in patients with low-risk myelodysplastic syndrome: two case reports
by: Fernando Barroso Duarte, et al.
Published: (2017-05-01)

Rare case of myelodysplastic syndrome with near-tetraploidy and TP53 mutation
by: Čolović Nataša, et al.
Published: (2023-01-01)

Δ133p53/FLp53 Predicts Poor Clinical Outcome in Esophageal Squamous Cell Carcinoma
by: Tu Q, et al.
Published: (2020-08-01)

Construction and Validation of an Immune-Related Prognostic Model Based on TP53 Status in Colorectal Cancer
by: Xiaojuan Zhao, et al.
Published: (2019-11-01)

Mesonephric Adenocarcinoma of the Vagina Harboring <i>TP53</i> Mutation
by: Hyunjee Lee, et al.
Published: (2022-01-01)

Characterizing isoform switching events in esophageal adenocarcinoma
by: Yun Zhang, et al.
Published: (2022-09-01)

TP53 /KRAS Co-Mutations Create Divergent Prognosis Signatures in Intrahepatic Cholangiocarcinoma
by: Chunguang Guo, et al.
Published: (2022-03-01)

TP53 Mutational Status-Based Genomic Signature for Prognosis and Predicting Therapeutic Response in Pancreatic Cancer
by: Feng Zhang, et al.
Published: (2021-05-01)

TP53 and TP53-associated genes are correlated with the prognosis of paediatric neuroblastoma
by: Haiwei Wang, et al.
Published: (2022-06-01)

<i>TP53</i> Mutation as a Prognostic and Predictive Marker in Sarcoma: Pooled Analysis of MOSCATO and ProfiLER Precision Medicine Trials
by: Elise F. Nassif, et al.
Published: (2021-07-01)

Effects of the Mutant TP53 Reactivator APR-246 on Therapeutic Sensitivity of Pancreatic Cancer Cells in the Presence and Absence of WT-TP53
by: Stephen L. Abrams, et al.
Published: (2022-02-01)

Searching for a cut-off point for p53 immunohistochemistry as evidence of TP53 mutations
by: Ilay Caliskan, et al.
Published: (2024-03-01)

Clinical outcomes and characteristics of patients with TP53-mutated myelodysplastic syndromes
by: Lijuan Zhang, et al.
Published: (2023-12-01)

Somatic intronic TP53 c.375+5G mutations are a recurrent but under‐recognized mode of TP53 inactivation
by: M Herman Chui, et al.
Published: (2022-01-01)

Comprehensive analysis of TP53 and SPOP mutations and their impact on survival in metastatic prostate cancer
by: Jie Zhou, et al.
Published: (2022-08-01)

TP53 GENE MUTATIONS – FROM GUARDIAN OF THE GENOME TO ONCOGENE
by: Petar Babović, et al.
Published: (2010-03-01)

Bone Marrow Fibrosis at Diagnosis and during the Course of Disease Is Associated with TP53 Mutations and Adverse Prognosis in Primary Myelodysplastic Syndrome
by: Youshan Zhao, et al.
Published: (2022-06-01)

Significance of TP53 mutation in bladder cancer disease progression and drug selection
by: Guang Wu, et al.
Published: (2019-12-01)

TP53 mutations predict poor response to immunotherapy in patients with metastatic solid tumors
by: Ji‐Yeon Kim, et al.
Published: (2023-06-01)

The prognosis of TP53 and EGFR co-mutation in patients with advanced lung adenocarcinoma and intracranial metastasis treated with EGFR-TKIs
by: Weiguo Gu, et al.
Published: (2024-02-01)

The prognostic value of TP53 mutations in hypopharyngeal squamous cell carcinoma
by: Go Omura, et al.
Published: (2017-12-01)

<i>TP53</i> Combined Phenotype Score Is Associated with the Clinical Outcome of <i>TP53</i>-Mutated Myelodysplastic Syndromes
by: Mariko Yabe, et al.
Published: (2021-11-01)

TP53-Deficient Angiosarcoma Expression Profiling in Rat Model
by: Urszula Smyczyńska, et al.
Published: (2020-06-01)

p53 immunostaining pattern is a useful surrogate marker for TP53 gene mutations
by: You-Na Sung, et al.
Published: (2022-12-01)

An integrated analysis revealing the angiogenic function of TP53I11 in tumor microenvironment
by: Wen Bai, et al.
Published: (2024-04-01)

A novel strategy for precise prognosis management and treatment option in colon adenocarcinoma with TP53 mutations
by: Lei Niu, et al.
Published: (2023-02-01)

Association of mRNA expression of TP53 and the TP53 codon 72 Arg/Pro gene polymorphism with colorectal cancer risk in Asian population: a bioinformatics analysis and meta-analysis
by: Dong ZY, et al.
Published: (2018-05-01)

Individualized prognosis stratification in muscle invasive bladder cancer: A pairwise TP53-derived transcriptome signature
by: Hua-Ping Liu, et al.
Published: (2023-03-01)

STRAP as a New Therapeutic Target for Poor Prognosis of Pancreatic Ductal Adenocarcinoma Patients Mainly Caused by TP53 Mutation
by: Shanshan Hu, et al.
Published: (2020-09-01)