Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation.

Diet-related metabolic syndrome is the largest contributor to adverse health in the United States. However, the study of gene-environment interactions and their epigenomic and transcriptomic integration is complicated by the lack of environmental and genetic control in humans that is possible in mou...

Full description

Bibliographic Details
Main Authors: Phillip Wulfridge, Adam Davidovich, Anna C Salvador, Gabrielle C Manno, Rakel Tryggvadottir, Adrian Idrizi, M Nazmul Huda, Brian J Bennett, L Garry Adams, Kasper D Hansen, David W Threadgill, Andrew P Feinberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-10-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010997&type=printable

Similar Items