Probiotic Ameliorating Effects of Altered GABA/Glutamate Signaling in a Rodent Model of Autism

Probiotic Ameliorating Effects of Altered GABA/Glutamate Signaling in a Rodent Model of Autism

Autism spectrum disorders (ASDs) comprise a heterogeneous group of pathological conditions, mainly of genetic origin, characterized by stereotyped behavior, such as marked impairment in verbal and nonverbal communication, social skills, and cognition. Excitatory/inhibitory (E/I) imbalances have been...

Full description

Bibliographic Details
Main Authors:	Rawan M. Bin-Khattaf, Mona A. Alonazi, Abeer M. Al-Dbass, Ahmad T. Almnaizel, Hisham S. Aloudah, Dina A. Soliman, Afaf K. El-Ansary
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Series:	Metabolites
Subjects:	autism spectrum disorders propionic acid oxidative stress glutamate excitotoxicity γ-aminobutyric acid GABA receptors
Online Access:	https://www.mdpi.com/2218-1989/12/8/720

Similar Items

Unveiling microbial dynamics in terasi spontaneous fermentation: Insights into glutamate and GABA production
by: Gemilang Lara Utama, et al.
Published: (2025-01-01)

In a rodent model of autism, probiotics decrease gut leakiness in relation to gene expression of GABA receptors: Emphasize how crucial the gut–brain axis
by: Bin-Khattaf Rawan M., et al.
Published: (2024-10-01)

The use of deuterium-labeled gamma-aminobutyric (D6-GABA) to study uptake, translocation, and metabolism of exogenous GABA in plants
by: Faraj Hijaz, et al.
Published: (2020-02-01)

Advances in Plant GABA Research: Biological Functions, Synthesis Mechanisms and Regulatory Pathways
by: Yixuan Hu, et al.
Published: (2024-10-01)

Calcium Involved in the Enrichment of γ-Aminobutyric Acid (GABA) in Broccoli Sprouts under Fructose Treatment
by: Qinling Wei, et al.
Published: (2023-01-01)

Examining the Role of GLU/GABA to GLN Metabolic Cycle in the Pathogenesis of Post-Stroke Depressive Disorder and Insomnia
by: Zhang XH, et al.
Published: (2023-12-01)

The role of GABA in islet function
by: D. Walker Hagan, et al.
Published: (2022-09-01)

Erratum: The role of GABA in islet function
by: Frontiers Production Office
Published: (2023-10-01)

Glutamate Decarboxylase from Lactic Acid Bacteria—A Key Enzyme in GABA Synthesis
by: Ida Bagus Agung Yogeswara, et al.
Published: (2020-12-01)

Evaluation of commercial soy sauce koji strains of Aspergillus oryzae for γ-aminobutyric acid (GABA) production
by: Ab Kadir, Safuan, et al.
Published: (2016)

Effect of Exogenous γ-Aminobutyric Acid (GABA) on the Growth, Photosynthetic Pigment, Antioxidant and GABA Metabolism of <i>Festuca arundinacea</i> (Tall Fescues) Under Cadmium Stress
by: Wan Geng, et al.
Published: (2025-01-01)

Effects of Red-Bean Tempeh with Various Strains of <i>Rhizopus</i> on GABA Content and Cortisol Level in Zebrafish
by: Yo-Chia Chen, et al.
Published: (2020-08-01)

Silkworm Pupae Coupled with Glucose Control pH Mediates GABA Hyperproduction by <i>Lactobacillus hilgardii</i>
by: Luchan Gong, et al.
Published: (2023-07-01)

Use of Selected Lactobacilli to Increase γ-Aminobutyric Acid (GABA) Content in Sourdough Bread Enriched with Amaranth Flour
by: Manuel Venturi, et al.
Published: (2019-06-01)

Isolation and selection of γ-aminobutyric acid producing lactic acid bacteria and application in GABA-enriched tomato juice fermentation
by: Le Quoc Viet, et al.
Published: (2024-08-01)

Methylenetetrahydrofolate reductase deficiency alters levels of glutamate and γ-aminobutyric acid in brain tissue
by: N.M. Jadavji, et al.
Published: (2015-06-01)

Quantifying GABA in Addiction: A Review of Proton Magnetic Resonance Spectroscopy Studies
by: Claire Shyu, et al.
Published: (2022-07-01)

Emerging Roles of γ Aminobutyric Acid (GABA) Gated Channels in Plant Stress Tolerance
by: Mona Kaspal, et al.
Published: (2021-10-01)

The Role of the <i>γ</i>-Aminobutyric Acid (GABA) in Plant Salt Stress Tolerance
by: Siarhei A. Dabravolski, et al.
Published: (2023-02-01)

Exogenous Application of GABA Alleviates Alkali Damage in Alfalfa by Increasing the Activities of Antioxidant Enzymes
by: Donghuan Li, et al.
Published: (2022-06-01)

Reduced GABA Levels in the ACC of Actively Drinking High Risk Individuals Compared to Recently Detoxified Alcohol-Dependent Patients
by: Gianna Spitta, et al.
Published: (2024-10-01)

Effect and Process Conditions of Cold Plasma Combined withL-Glutamic Acid and Salt Stress on Germination and Enrichment ofγ-Aminobutyric Acid in Adzuki Bean
by: Qingpeng XU, et al.
Published: (2023-11-01)

Site‐directed mutagenesis improves the practical application of L‐glutamic acid decarboxylase in Escherichia coli
by: Liu Fengmin, et al.
Published: (2023-04-01)

The γ-Aminobutyric Acid (GABA) Synthesis Gene Regulates the Resistance to Water Core-Induced Hypoxia Stress for Pear Fruits
by: Xiao Liu, et al.
Published: (2023-04-01)

Capacitation of mouse sperm is modulated by gamma-aminobutyric acid (GABA) concentration
by: Shouhei KURATA, et al.
Published: (2019-06-01)

Drosophila melanogaster as a model for unraveling unique molecular features of epilepsy elicited by human GABA transporter 1 variants
by: Ameya S. Kasture, et al.
Published: (2023-01-01)

Astrocytes Maintain Glutamate Homeostasis in the CNS by Controlling the Balance between Glutamate Uptake and Release
by: Shaimaa Mahmoud, et al.
Published: (2019-02-01)

A Novel Method for γ-Aminobutyric Acid Biosynthesis Using Glutamate Decarboxylase Entrapped in Polyvinyl Alcohol–Sodium Alginate Capsules
by: Fei Zhu, et al.
Published: (2023-09-01)

Detection of physiological concentrations of GABA using dielectric spectroscopy - A pilot study
by: Hou Jie, et al.
Published: (2023-12-01)

High-level production of γ-aminobutyric acid via efficient co-expression of the key genes of glutamate decarboxylase system in Escherichia coli
by: Lili Yao, et al.
Published: (2023-06-01)

KangPiLao decoction modulates cognitive and emotional disorders in rats with central fatigue through the GABA/Glu pathway
by: Yifei Xu, et al.
Published: (2022-09-01)

Novel fermented chickpea milk with enhanced level of γ-aminobutyric acid and neuroprotective effect on PC12 cells
by: Wen Li, et al.
Published: (2016-08-01)

Characterization of the Gamma-Aminobutyric Acid (GABA) Biosynthetic Gene Cluster in High GABA-Producing <i>Enterococcus avium</i> G-15
by: Masafumi Noda, et al.
Published: (2024-07-01)

Epigenetic regulation of neurotransmitter signaling in neurological disorders
by: Tingyan Wu, et al.
Published: (2023-08-01)

Effects of GABA seed priming on alleviating salt stress and physiological and biochemical changes in Capsicum annuum
by: Xinqi LIN, et al.
Published: (2023-12-01)

Interplay between microbial‐derived GABA and host GABA receptor signaling collectively influence the tumorigenic function of GABA in colon cancer
by: Jonathan M. Keane, et al.
Published: (2024-08-01)

Unveiling sex-based differences in developing propionic acid-induced features in mice as a rodent model of ASD
by: Nasreen Kamalmaz, et al.
Published: (2023-06-01)

GABA: a key player of abiotic stress regulation
by: Vipul Mishra, et al.
Published: (2023-12-01)

High Expression of GABA<sub>A</sub> Receptor β Subunit Genes Is Associated with Longer Overall Survival in Medulloblastoma
by: Jander M. Monteiro, et al.
Published: (2024-11-01)

Optimisation of Fermentative Parameters for GABA Enrichment by Lactococcus lactis
by: XiaoXue Lu, et al.
Published: (2009-12-01)