Appropriate design and reporting of superiority, equivalence and non-inferiority clinical trials incorporating a benefit–risk assessment: the BRAINS study including expert workshop

Appropriate design and reporting of superiority, equivalence and non-inferiority clinical trials incorporating a benefit–risk assessment: the BRAINS study including expert workshop

Background Randomised controlled trials are designed to assess the superiority, equivalence or non-inferiority of a new health technology, but which trial design should be used is not always obvious in practice. In particular, when using equivalence or non-inferiority designs, multiple outcomes of i...

Full description

Bibliographic Details
Main Authors: Nikki Totton, Steven A Julious, Elizabeth Coates, Dyfrig A Hughes, Jonathan A Cook, Katie Biggs, Catherine Hewitt, Simon Day, Andrew Cook
Format: Article
Language:English
Published: NIHR Journals Library 2023-10-01
Series:Health Technology Assessment
Subjects:
benefit–risk
superiority
non-inferiority
equivalence
clinical trials
Online Access:https://doi.org/10.3310/BHQZ7691

Similar Items

Similar Items