Cell Reprogramming to Model Huntington’s Disease: A Comprehensive Review

Cell Reprogramming to Model Huntington’s Disease: A Comprehensive Review

Huntington’s disease (HD) is a neurodegenerative disorder characterized by the progressive decline of motor, cognitive, and psychiatric functions. HD results from an autosomal dominant mutation that causes a trinucleotide CAG repeat expansion and the production of mutant Huntingtin protein (mHTT). T...

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Bibliographic Details
Main Authors:	Ruth Monk, Bronwen Connor
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Series:	Cells
Subjects:	cell reprogramming pluripotent stem cells direct cell reprogramming disease modelling Huntington’s disease striatal differentiation
Online Access:	https://www.mdpi.com/2073-4409/10/7/1565

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