Biocatalytic route scouting and enzyme screening toward the synthesis of α-benzyl L-glutamate
We here report four biocatalytic approaches for the synthesis of the protected amino acid building block α-benzyl L-glutamate. Screenings of these routes to identify active and selective enzymes were conducted, and major hits were confirmed in retest reactions. In the first approach, N-Boc L-glutami...
Main Authors: | Peter J. L. M. Quaedflieg, Lisanne M. H. Jente, Monika Müller, Linda Vermote, Victor Plesciuc, Jan-Metske van der Laan, Lone Nielsen, Martin Schürmann |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2024-01-01
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Series: | Frontiers in Catalysis |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fctls.2023.1285074/full |
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