Evaluation of Avian Reovirus S1133 Vaccine Strain in Neonatal Broiler Chickens in Gastrointestinal Integrity and Performance in a Large-Scale Commercial Field Trial
Avian reovirus (ARV) is the principal cause of several diseases. The vaccination of breeders allows for the control of viral arthritis and delivery of maternal-derived antibodies to the progeny. The vaccination of broiler chickens with ARV strain S1133 is used to prevent viral arthritis. However, th...
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| Format: | Article |
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MDPI AG
2021-07-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/9/8/817 |
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| author | Victor Manuel Petrone-Garcia Joshua Gonzalez-Soto Raquel Lopez-Arellano Mariano Delgadillo-Gonzalez Victor M. Valdes-Narvaez Fernando Alba-Hurtado Xochitl Hernandez-Velasco Inkar Castellanos-Huerta Guillermo Tellez-Isaias |
| author_facet | Victor Manuel Petrone-Garcia Joshua Gonzalez-Soto Raquel Lopez-Arellano Mariano Delgadillo-Gonzalez Victor M. Valdes-Narvaez Fernando Alba-Hurtado Xochitl Hernandez-Velasco Inkar Castellanos-Huerta Guillermo Tellez-Isaias |
| author_sort | Victor Manuel Petrone-Garcia |
| collection | DOAJ |
| description | Avian reovirus (ARV) is the principal cause of several diseases. The vaccination of breeders allows for the control of viral arthritis and delivery of maternal-derived antibodies to the progeny. The vaccination of broiler chickens with ARV strain S1133 is used to prevent viral arthritis. However, the post-vaccination enteric effects have not been well-characterized. The purpose of this study was to evaluate the effect of vaccination with the S1133 strain on the weight gain and feed conversion of broiler chickens and to characterize the gastric, enteric, and pancreatic lesions that the strain could induce. A total of 672,000 chickens were divided into two groups: a group vaccinated with ARV strain S1133 (S1133ARV) and a control group (not vaccinated). Upon histological analysis, the vaccine group showed less proventricular glandular tissue and atrophy of the pancreas and duodenal villi, as well as having a lower average daily profit. The conclusion based on the results of this investigation is that neonatal vaccination with S1133ARV causes atrophy of the pancreatic acini, proventricular glands, and intestinal villi, leading to an increased diameter of the glandular lumen and atrophy of the enteric villous, as well as weight loss, in broiler chickens. |
| first_indexed | 2024-03-10T08:19:32Z |
| format | Article |
| id | doaj.art-605df666d7004ab0a407353b002aa4c9 |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-10T08:19:32Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-605df666d7004ab0a407353b002aa4c92023-11-22T10:06:21ZengMDPI AGVaccines2076-393X2021-07-019881710.3390/vaccines9080817Evaluation of Avian Reovirus S1133 Vaccine Strain in Neonatal Broiler Chickens in Gastrointestinal Integrity and Performance in a Large-Scale Commercial Field TrialVictor Manuel Petrone-Garcia0Joshua Gonzalez-Soto1Raquel Lopez-Arellano2Mariano Delgadillo-Gonzalez3Victor M. Valdes-Narvaez4Fernando Alba-Hurtado5Xochitl Hernandez-Velasco6Inkar Castellanos-Huerta7Guillermo Tellez-Isaias8Programa de Doctorado en Ciencias de la Salud y Producción Animal, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico, Cuautitlán Izcalli 54714, MexicoDepartamento de Ciencias Biológicas, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico, Cuautitlán Izcalli 54714, MexicoLaboratorio No 5: LEDEFAR, Unidad de Investigacion Multidisciplinaria, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico, Cuautitlán Izcalli 54714, MexicoIndependent Poultry Zootechnical, Aguascalientes 20000, MexicoIndependent Poultry Nutritionist, Texcoco 56100, MexicoDepartamento de Ciencias Biológicas, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico, Cuautitlán Izcalli 54714, MexicoDepartamento de Medicina y Zootecnia de Aves, Facultad de Medicina Veterinaria y Zootecnia, UNAM, Coyoacan 04510, MexicoPrograma de Doctorado en Ciencias de la Salud y Producción Animal, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico, Cuautitlán Izcalli 54714, MexicoDepartment of Poultry Science, University of Arkansas, Fayetteville, NC 72701, USAAvian reovirus (ARV) is the principal cause of several diseases. The vaccination of breeders allows for the control of viral arthritis and delivery of maternal-derived antibodies to the progeny. The vaccination of broiler chickens with ARV strain S1133 is used to prevent viral arthritis. However, the post-vaccination enteric effects have not been well-characterized. The purpose of this study was to evaluate the effect of vaccination with the S1133 strain on the weight gain and feed conversion of broiler chickens and to characterize the gastric, enteric, and pancreatic lesions that the strain could induce. A total of 672,000 chickens were divided into two groups: a group vaccinated with ARV strain S1133 (S1133ARV) and a control group (not vaccinated). Upon histological analysis, the vaccine group showed less proventricular glandular tissue and atrophy of the pancreas and duodenal villi, as well as having a lower average daily profit. The conclusion based on the results of this investigation is that neonatal vaccination with S1133ARV causes atrophy of the pancreatic acini, proventricular glands, and intestinal villi, leading to an increased diameter of the glandular lumen and atrophy of the enteric villous, as well as weight loss, in broiler chickens.https://www.mdpi.com/2076-393X/9/8/817reovirus S1133 vaccinepancreatic and enteric histologyELISA |
| spellingShingle | Victor Manuel Petrone-Garcia Joshua Gonzalez-Soto Raquel Lopez-Arellano Mariano Delgadillo-Gonzalez Victor M. Valdes-Narvaez Fernando Alba-Hurtado Xochitl Hernandez-Velasco Inkar Castellanos-Huerta Guillermo Tellez-Isaias Evaluation of Avian Reovirus S1133 Vaccine Strain in Neonatal Broiler Chickens in Gastrointestinal Integrity and Performance in a Large-Scale Commercial Field Trial Vaccines reovirus S1133 vaccine pancreatic and enteric histology ELISA |
| title | Evaluation of Avian Reovirus S1133 Vaccine Strain in Neonatal Broiler Chickens in Gastrointestinal Integrity and Performance in a Large-Scale Commercial Field Trial |
| title_full | Evaluation of Avian Reovirus S1133 Vaccine Strain in Neonatal Broiler Chickens in Gastrointestinal Integrity and Performance in a Large-Scale Commercial Field Trial |
| title_fullStr | Evaluation of Avian Reovirus S1133 Vaccine Strain in Neonatal Broiler Chickens in Gastrointestinal Integrity and Performance in a Large-Scale Commercial Field Trial |
| title_full_unstemmed | Evaluation of Avian Reovirus S1133 Vaccine Strain in Neonatal Broiler Chickens in Gastrointestinal Integrity and Performance in a Large-Scale Commercial Field Trial |
| title_short | Evaluation of Avian Reovirus S1133 Vaccine Strain in Neonatal Broiler Chickens in Gastrointestinal Integrity and Performance in a Large-Scale Commercial Field Trial |
| title_sort | evaluation of avian reovirus s1133 vaccine strain in neonatal broiler chickens in gastrointestinal integrity and performance in a large scale commercial field trial |
| topic | reovirus S1133 vaccine pancreatic and enteric histology ELISA |
| url | https://www.mdpi.com/2076-393X/9/8/817 |
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