Oxidized phospholipids, linked to apolipoprotein B of oxidized LDL, are ligands for macrophage scavenger receptors

Oxidized phospholipids, linked to apolipoprotein B of oxidized LDL, are ligands for macrophage scavenger receptors

Previous studies have shown that macrophage receptors for oxidized LDL (OxLDL) recognize both the lipid and protein moieties, and that a monoclonal antibody against OxLDL, EO6, also recognizes both species. The present studies show directly that during LDL oxidation phospholipids become covalently a...

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Bibliographic Details
Main Authors: Kristin L. Gillotte, Sohvi Hörkkö, Joseph L. Witztum, Daniel Steinberg
Format: Article
Language:English
Published: Elsevier 2000-05-01
Series:Journal of Lipid Research
Subjects:
oxidized phospholipid
oxidized LDL
apolipoprotein B
scavenger receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520323919

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