Cytoxicity and apoptotic mechanism of ruthenium(II) amino acid complexes in sarcoma-180 tumor cells.

Cytoxicity and apoptotic mechanism of ruthenium(II) amino acid complexes in sarcoma-180 tumor cells.

Over the past several decades, much attention has been focused on ruthenium complexes in antitumor therapy. Ruthenium is a transition metal that possesses several advantages for rational antitumor drug design and biological applications. In the present study, five ruthenium complexes containing amin...

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Bibliographic Details
Main Authors: Aliny Pereira Lima, Flávia Castro Pereira, Marcio Aurelio Pinheiro Almeida, Francyelli Mariana Santos Mello, Wanessa Carvalho Pires, Thallita Monteiro Pinto, Flávia Karina Delella, Sérgio Luis Felisbino, Virtudes Moreno, Alzir Azevedo Batista, Elisângela de Paula Silveira-Lacerda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4201456?pdf=render

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