Single nucleotide polymorphisms in surfactant protein A1 are not associated with a lack of responsiveness to antenatal steroid therapy in a pregnant sheep model

Single nucleotide polymorphisms in surfactant protein A1 are not associated with a lack of responsiveness to antenatal steroid therapy in a pregnant sheep model

Abstract Treatment with antenatal steroids (ANS) is standard practice for reducing the risk of respiratory distress in the preterm infant. Despite clear overall benefits when appropriately administered, many fetuses fail to derive benefit from ANS therapies. In standardized experiments using a pregn...

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Bibliographic Details
Main Authors: Tsukasa Takahashi, Yuki Takahashi, Erin L. Fee, Haruo Usuda, Lucy Furfaro, John P. Newnham, Alan H. Jobe, Matthew W. Kemp
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Physiological Reports
Subjects:
antenatal corticosteroids
lung maturation
preterm birth
sheep
single nucleotide polymorphisms
Online Access:https://doi.org/10.14814/phy2.15477

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