The Effectiveness of Interventions for Increasing COVID-19 Vaccine Uptake: A Systematic Review

Vaccination is vital to protect the public against COVID-19. The aim of this systematic review is to identify and evaluate the effectiveness of interventions to increase COVID-19 vaccine uptake. We searched a range of databases (Embase, Medline, Psychology & Behavioral Science, PsycInfo, Web of...

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Main Authors: Eleonore Batteux, Freya Mills, Leah Ffion Jones, Charles Symons, Dale Weston
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/10/3/386
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author Eleonore Batteux
Freya Mills
Leah Ffion Jones
Charles Symons
Dale Weston
author_facet Eleonore Batteux
Freya Mills
Leah Ffion Jones
Charles Symons
Dale Weston
author_sort Eleonore Batteux
collection DOAJ
description Vaccination is vital to protect the public against COVID-19. The aim of this systematic review is to identify and evaluate the effectiveness of interventions to increase COVID-19 vaccine uptake. We searched a range of databases (Embase, Medline, Psychology & Behavioral Science, PsycInfo, Web of Science and NIH Preprints Portfolio) from March 2020 to July 2021 for studies which reported primary quantitative or qualitative research on interventions to increase COVID-19 vaccine uptake. Outcome measures included vaccination uptake and reported intention to vaccinate. Reviews, position papers, conference abstracts, protocol papers and papers not in English were excluded. The NHLBI quality assessment was used to assess risk of bias. In total, 39 studies across 33 papers met the inclusion criteria. A total of 28 were assessed as good quality. They included interventions relating to communication content, communication delivery, communication presentation, policy or vaccination delivery, with 7 measuring vaccination uptake and 32 measuring vaccination intention. A narrative synthesis was conducted, which highlighted that there is reasonable evidence from studies investigating real behaviour suggesting that personalising communications and sending booking reminders via text message increases vaccine uptake. Findings on vaccination intention are mixed but suggest that communicating uncertainty about the vaccine does not decrease intention, whereas making vaccination mandatory could have a negative impact. Although much of the research used experimental designs, very few measured real behavioural outcomes. Understanding which interventions are most effective amongst vaccine-hesitant populations and in the context of booster vaccinations will be important as vaccine roll outs continue across the world.
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spelling doaj.art-6060bcda6f374a8eab498b0e0619b5e02023-11-30T22:42:14ZengMDPI AGVaccines2076-393X2022-03-0110338610.3390/vaccines10030386The Effectiveness of Interventions for Increasing COVID-19 Vaccine Uptake: A Systematic ReviewEleonore Batteux0Freya Mills1Leah Ffion Jones2Charles Symons3Dale Weston4Behavioural Science and Insights Unit, UK Health Security Agency, Salisbury SP4 0JG, UKBehavioural Science and Insights Unit, UK Health Security Agency, Salisbury SP4 0JG, UKBehavioural Science and Insights Unit, UK Health Security Agency, Salisbury SP4 0JG, UKBehavioural Science and Insights Unit, UK Health Security Agency, Salisbury SP4 0JG, UKBehavioural Science and Insights Unit, UK Health Security Agency, Salisbury SP4 0JG, UKVaccination is vital to protect the public against COVID-19. The aim of this systematic review is to identify and evaluate the effectiveness of interventions to increase COVID-19 vaccine uptake. We searched a range of databases (Embase, Medline, Psychology & Behavioral Science, PsycInfo, Web of Science and NIH Preprints Portfolio) from March 2020 to July 2021 for studies which reported primary quantitative or qualitative research on interventions to increase COVID-19 vaccine uptake. Outcome measures included vaccination uptake and reported intention to vaccinate. Reviews, position papers, conference abstracts, protocol papers and papers not in English were excluded. The NHLBI quality assessment was used to assess risk of bias. In total, 39 studies across 33 papers met the inclusion criteria. A total of 28 were assessed as good quality. They included interventions relating to communication content, communication delivery, communication presentation, policy or vaccination delivery, with 7 measuring vaccination uptake and 32 measuring vaccination intention. A narrative synthesis was conducted, which highlighted that there is reasonable evidence from studies investigating real behaviour suggesting that personalising communications and sending booking reminders via text message increases vaccine uptake. Findings on vaccination intention are mixed but suggest that communicating uncertainty about the vaccine does not decrease intention, whereas making vaccination mandatory could have a negative impact. Although much of the research used experimental designs, very few measured real behavioural outcomes. Understanding which interventions are most effective amongst vaccine-hesitant populations and in the context of booster vaccinations will be important as vaccine roll outs continue across the world.https://www.mdpi.com/2076-393X/10/3/386COVID-19vaccinesvaccine uptakesystematic reviewinterventionsbehaviour change
spellingShingle Eleonore Batteux
Freya Mills
Leah Ffion Jones
Charles Symons
Dale Weston
The Effectiveness of Interventions for Increasing COVID-19 Vaccine Uptake: A Systematic Review
Vaccines
COVID-19
vaccines
vaccine uptake
systematic review
interventions
behaviour change
title The Effectiveness of Interventions for Increasing COVID-19 Vaccine Uptake: A Systematic Review
title_full The Effectiveness of Interventions for Increasing COVID-19 Vaccine Uptake: A Systematic Review
title_fullStr The Effectiveness of Interventions for Increasing COVID-19 Vaccine Uptake: A Systematic Review
title_full_unstemmed The Effectiveness of Interventions for Increasing COVID-19 Vaccine Uptake: A Systematic Review
title_short The Effectiveness of Interventions for Increasing COVID-19 Vaccine Uptake: A Systematic Review
title_sort effectiveness of interventions for increasing covid 19 vaccine uptake a systematic review
topic COVID-19
vaccines
vaccine uptake
systematic review
interventions
behaviour change
url https://www.mdpi.com/2076-393X/10/3/386
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