Flavonoid-rich foods (FRF): A promising nutraceutical approach against lifespan-shortening diseases
It is well documented that life expectancy in developed countries at birth is going to increase from the 20th century. However, regrettably, a potential decline in life expectancy has been proposed for these nations in the 21st century due to a rapid upsurge in the prevalence of fatal degenerative d...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2020-02-01
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| Series: | Iranian Journal of Basic Medical Sciences |
| Subjects: | |
| Online Access: | http://ijbms.mums.ac.ir/article_14327_84f5823cad59043095e379aaec9f7c45.pdf |
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| author | Alhamzah Hasan Waheed Janabi Asghar Ali Kamboh Muhammad Saeed Lu Xiaoyu Jannat BiBi Fatima Majeed Muhammad Naveed Muhammad Jameel Mughal Nazar Ali Korejo Rubina Kamboh Mahmoud Alagawany Lv Huixia |
| author_facet | Alhamzah Hasan Waheed Janabi Asghar Ali Kamboh Muhammad Saeed Lu Xiaoyu Jannat BiBi Fatima Majeed Muhammad Naveed Muhammad Jameel Mughal Nazar Ali Korejo Rubina Kamboh Mahmoud Alagawany Lv Huixia |
| author_sort | Alhamzah Hasan Waheed Janabi |
| collection | DOAJ |
| description | It is well documented that life expectancy in developed countries at birth is going to increase from the 20th century. However, regrettably, a potential decline in life expectancy has been proposed for these nations in the 21st century due to a rapid upsurge in the prevalence of fatal degenerative diseases like cardiovascular diseases (CVD), cancer and diabetes. Collectively, these three diseases accounted for 65% of all deaths in urbanized societies and considered as a dynamic issue for shortening the genetically determined lifespan through increased mortalities, morbidities, disabilities, immense sufferings, and premature aging. These fatal degenerative diseases and premature aging are closely associated with oxidative stress produced by the free radicals in the body. In epidemiologic studies, flavonoid-rich foods (FRF) like fruits, vegetables, and beverages have been associated as protective agents against these diseases. These also have been observed for their geroprotective effects and help in preventing the premature aging and the deterioration of brain function, which is related to Alzheimer’s disease and dementia. In this review, we presented a comprehensive overview of the FRF for their potential role against lifespan-shortening complications, i.e., CVD, cancer, and diabetes. We also had drawn the future perspective and dietary guidelines to reduce the fatal diseases burden in urban populations. |
| first_indexed | 2024-04-12T19:11:08Z |
| format | Article |
| id | doaj.art-6063bf741a0444f1a2f59cece452ecde |
| institution | Directory Open Access Journal |
| issn | 2008-3866 2008-3874 |
| language | English |
| last_indexed | 2024-04-12T19:11:08Z |
| publishDate | 2020-02-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Basic Medical Sciences |
| spelling | doaj.art-6063bf741a0444f1a2f59cece452ecde2022-12-22T03:19:53ZengMashhad University of Medical SciencesIranian Journal of Basic Medical Sciences2008-38662008-38742020-02-0123214015310.22038/ijbms.2019.35125.835314327Flavonoid-rich foods (FRF): A promising nutraceutical approach against lifespan-shortening diseasesAlhamzah Hasan Waheed Janabi0Asghar Ali Kamboh1Muhammad Saeed2Lu Xiaoyu3Jannat BiBi4Fatima Majeed5Muhammad Naveed6Muhammad Jameel Mughal7Nazar Ali Korejo8Rubina Kamboh9Mahmoud Alagawany10Lv Huixia11State Key Laboratory of Natural Medicines, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, Jiangsu Province, PR ChinaDepartment of Veterinary Microbiology, Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University Tandojam 70060, PakistanFaculty of Animal Production and Technology, Cholistan University of Veterinary and Animal Sciences, Bahawalpur 6300, PakistanState Key Laboratory of Natural Medicines, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, Jiangsu Province, PR ChinaDepartment of Physical Education, Shaanxi Normal University, Xian, Shaanxi Province, P.R ChinaSchool of Public Health, Nanjing Medical University, Jiangsu Province, 211166, P.R ChinaSchool of Pharmacy, Nanjing Medical University, Jiangsu Province, 211166, P.R ChinaFaculty of Health Sciences, University of Macau, Avenida de UniversidadeTaipa, MacauDepartment of Veterinary Medicine, Faculty of Animal Husbandry and Veterinary Science, Sindh Agriculture University, Tandojam 70060, PakistanLiaquat University of Medical and Health Sciences, Jamshoro, PakistanDepartmentof Poultry, Faculty of Agriculture, Zagazig University, Zagazig 44511, EgyptState Key Laboratory of Natural Medicines, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, Jiangsu Province, PR ChinaIt is well documented that life expectancy in developed countries at birth is going to increase from the 20th century. However, regrettably, a potential decline in life expectancy has been proposed for these nations in the 21st century due to a rapid upsurge in the prevalence of fatal degenerative diseases like cardiovascular diseases (CVD), cancer and diabetes. Collectively, these three diseases accounted for 65% of all deaths in urbanized societies and considered as a dynamic issue for shortening the genetically determined lifespan through increased mortalities, morbidities, disabilities, immense sufferings, and premature aging. These fatal degenerative diseases and premature aging are closely associated with oxidative stress produced by the free radicals in the body. In epidemiologic studies, flavonoid-rich foods (FRF) like fruits, vegetables, and beverages have been associated as protective agents against these diseases. These also have been observed for their geroprotective effects and help in preventing the premature aging and the deterioration of brain function, which is related to Alzheimer’s disease and dementia. In this review, we presented a comprehensive overview of the FRF for their potential role against lifespan-shortening complications, i.e., CVD, cancer, and diabetes. We also had drawn the future perspective and dietary guidelines to reduce the fatal diseases burden in urban populations.http://ijbms.mums.ac.ir/article_14327_84f5823cad59043095e379aaec9f7c45.pdfanti-oxidantscancers geroprotectivecardiovascular diseases diabetesdietary supplements nutraceuticals |
| spellingShingle | Alhamzah Hasan Waheed Janabi Asghar Ali Kamboh Muhammad Saeed Lu Xiaoyu Jannat BiBi Fatima Majeed Muhammad Naveed Muhammad Jameel Mughal Nazar Ali Korejo Rubina Kamboh Mahmoud Alagawany Lv Huixia Flavonoid-rich foods (FRF): A promising nutraceutical approach against lifespan-shortening diseases Iranian Journal of Basic Medical Sciences anti-oxidants cancers geroprotective cardiovascular diseases diabetes dietary supplements nutraceuticals |
| title | Flavonoid-rich foods (FRF): A promising nutraceutical approach against lifespan-shortening diseases |
| title_full | Flavonoid-rich foods (FRF): A promising nutraceutical approach against lifespan-shortening diseases |
| title_fullStr | Flavonoid-rich foods (FRF): A promising nutraceutical approach against lifespan-shortening diseases |
| title_full_unstemmed | Flavonoid-rich foods (FRF): A promising nutraceutical approach against lifespan-shortening diseases |
| title_short | Flavonoid-rich foods (FRF): A promising nutraceutical approach against lifespan-shortening diseases |
| title_sort | flavonoid rich foods frf a promising nutraceutical approach against lifespan shortening diseases |
| topic | anti-oxidants cancers geroprotective cardiovascular diseases diabetes dietary supplements nutraceuticals |
| url | http://ijbms.mums.ac.ir/article_14327_84f5823cad59043095e379aaec9f7c45.pdf |
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