Prevalence and Risk Factors of Chronic Kidney Disease in the General Population in Abidjan, Côte d'Ivoire: A Cross-sectional Study
Chronic kidney disease (CKD) is a major cause of morbidity and mortality worldwide, but few studies are available on CKD in Cote d'Ivoire. We aimed to assess the prevalence of CKD and identify its associated factors in the general population in Abidjan in 2016 in a cross-sectional study that in...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2023-03-01
|
| Series: | Saudi Journal of Kidney Diseases and Transplantation |
| Online Access: | https://journals.lww.com/10.4103/1319-2442.397204 |
| _version_ | 1827212581114216448 |
|---|---|
| author | Kouamé Hubert Yao Sery Patrick Diopoh Serge Didier Konan Monlet Cyr Guehi Sira Kamagate Kolo Ouattara Mohamed Ibrahim Alex Moudachirou |
| author_facet | Kouamé Hubert Yao Sery Patrick Diopoh Serge Didier Konan Monlet Cyr Guehi Sira Kamagate Kolo Ouattara Mohamed Ibrahim Alex Moudachirou |
| author_sort | Kouamé Hubert Yao |
| collection | DOAJ |
| description | Chronic kidney disease (CKD) is a major cause of morbidity and mortality worldwide, but few studies are available on CKD in Cote d'Ivoire. We aimed to assess the prevalence of CKD and identify its associated factors in the general population in Abidjan in 2016 in a cross-sectional study that included 1418 subjects. We did not receive laboratory data for 38 subjects, including serum creatinine data. Of the 1380 remaining subjects, 138 cases of CKD were included in the study (10% prevalence). We observed a female predominance (sex ratio = 0.81), and the mean age was 43.7 ± 14.5 years. Histories of hypertension (HTN) (29.7%) and diabetes (10.1%) were reported. The main clinical signs were high blood pressure (51.4%), obesity (21%), proteinuria (37.9%), and hematuria (37.4%). The glomerular filtration rate (GFR) was <60 mL/min in 8.2% of cases according to the Modification of Diet in Renal Disease equation, in 8.6% according to the CKD Epidemiology Collaboration equation, and in 12.6% according to the Cockroft-Gault (CG) equation. The other laboratory signs were hyperglycemia (51.4%), hypercholesterolemia (34.1%), and hyperlipidemia (21%). In the multivariate analysis, factors such as female sex (P = 0.013), age >55 years (P = 0.02), a history of HTN (P = 0.001), hypercholesterolemia (P = 0.010), and hyperlipidemia (P = 0.009) were associated with the risk of CKD. The prevalence of CKD was high in our study. The CG equation should not be used to estimate the GFR in the general population. Prevention involves managing modifiable risk factors. |
| first_indexed | 2024-04-24T19:36:20Z |
| format | Article |
| id | doaj.art-6067183c324545bcaeef39eeb50887dd |
| institution | Directory Open Access Journal |
| issn | 1319-2442 2320-3838 |
| language | English |
| last_indexed | 2025-03-21T14:01:49Z |
| publishDate | 2023-03-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Kidney Diseases and Transplantation |
| spelling | doaj.art-6067183c324545bcaeef39eeb50887dd2024-06-25T15:07:18ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422320-38382023-03-0134542743610.4103/1319-2442.397204Prevalence and Risk Factors of Chronic Kidney Disease in the General Population in Abidjan, Côte d'Ivoire: A Cross-sectional StudyKouamé Hubert YaoSery Patrick DiopohSerge Didier KonanMonlet Cyr GuehiSira KamagateKolo OuattaraMohamed Ibrahim Alex MoudachirouChronic kidney disease (CKD) is a major cause of morbidity and mortality worldwide, but few studies are available on CKD in Cote d'Ivoire. We aimed to assess the prevalence of CKD and identify its associated factors in the general population in Abidjan in 2016 in a cross-sectional study that included 1418 subjects. We did not receive laboratory data for 38 subjects, including serum creatinine data. Of the 1380 remaining subjects, 138 cases of CKD were included in the study (10% prevalence). We observed a female predominance (sex ratio = 0.81), and the mean age was 43.7 ± 14.5 years. Histories of hypertension (HTN) (29.7%) and diabetes (10.1%) were reported. The main clinical signs were high blood pressure (51.4%), obesity (21%), proteinuria (37.9%), and hematuria (37.4%). The glomerular filtration rate (GFR) was <60 mL/min in 8.2% of cases according to the Modification of Diet in Renal Disease equation, in 8.6% according to the CKD Epidemiology Collaboration equation, and in 12.6% according to the Cockroft-Gault (CG) equation. The other laboratory signs were hyperglycemia (51.4%), hypercholesterolemia (34.1%), and hyperlipidemia (21%). In the multivariate analysis, factors such as female sex (P = 0.013), age >55 years (P = 0.02), a history of HTN (P = 0.001), hypercholesterolemia (P = 0.010), and hyperlipidemia (P = 0.009) were associated with the risk of CKD. The prevalence of CKD was high in our study. The CG equation should not be used to estimate the GFR in the general population. Prevention involves managing modifiable risk factors.https://journals.lww.com/10.4103/1319-2442.397204 |
| spellingShingle | Kouamé Hubert Yao Sery Patrick Diopoh Serge Didier Konan Monlet Cyr Guehi Sira Kamagate Kolo Ouattara Mohamed Ibrahim Alex Moudachirou Prevalence and Risk Factors of Chronic Kidney Disease in the General Population in Abidjan, Côte d'Ivoire: A Cross-sectional Study Saudi Journal of Kidney Diseases and Transplantation |
| title | Prevalence and Risk Factors of Chronic Kidney Disease in the General Population in Abidjan, Côte d'Ivoire: A Cross-sectional Study |
| title_full | Prevalence and Risk Factors of Chronic Kidney Disease in the General Population in Abidjan, Côte d'Ivoire: A Cross-sectional Study |
| title_fullStr | Prevalence and Risk Factors of Chronic Kidney Disease in the General Population in Abidjan, Côte d'Ivoire: A Cross-sectional Study |
| title_full_unstemmed | Prevalence and Risk Factors of Chronic Kidney Disease in the General Population in Abidjan, Côte d'Ivoire: A Cross-sectional Study |
| title_short | Prevalence and Risk Factors of Chronic Kidney Disease in the General Population in Abidjan, Côte d'Ivoire: A Cross-sectional Study |
| title_sort | prevalence and risk factors of chronic kidney disease in the general population in abidjan cote d ivoire a cross sectional study |
| url | https://journals.lww.com/10.4103/1319-2442.397204 |
| work_keys_str_mv | AT kouamehubertyao prevalenceandriskfactorsofchronickidneydiseaseinthegeneralpopulationinabidjancotedivoireacrosssectionalstudy AT serypatrickdiopoh prevalenceandriskfactorsofchronickidneydiseaseinthegeneralpopulationinabidjancotedivoireacrosssectionalstudy AT sergedidierkonan prevalenceandriskfactorsofchronickidneydiseaseinthegeneralpopulationinabidjancotedivoireacrosssectionalstudy AT monletcyrguehi prevalenceandriskfactorsofchronickidneydiseaseinthegeneralpopulationinabidjancotedivoireacrosssectionalstudy AT sirakamagate prevalenceandriskfactorsofchronickidneydiseaseinthegeneralpopulationinabidjancotedivoireacrosssectionalstudy AT koloouattara prevalenceandriskfactorsofchronickidneydiseaseinthegeneralpopulationinabidjancotedivoireacrosssectionalstudy AT mohamedibrahimalexmoudachirou prevalenceandriskfactorsofchronickidneydiseaseinthegeneralpopulationinabidjancotedivoireacrosssectionalstudy |