Update on Diagnosis and Treatment of Uveitic Glaucoma
Glaucoma is a common and potentially blinding complication of uveitis. Many mechanisms are involved alone or in combination in the pathogenesis of uveitic glaucoma (UG). In terms of diagnostic evaluation, the effects of inflammatory activity in the retinal nerve fiber layer may be a source of bias i...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/13/5/1185 |
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| author | Ioannis Halkiadakis Kalliroi Konstantopoulou Vasilios Tzimis Nikolaos Papadopoulos Klio Chatzistefanou Nikolaos N. Markomichelakis |
| author_facet | Ioannis Halkiadakis Kalliroi Konstantopoulou Vasilios Tzimis Nikolaos Papadopoulos Klio Chatzistefanou Nikolaos N. Markomichelakis |
| author_sort | Ioannis Halkiadakis |
| collection | DOAJ |
| description | Glaucoma is a common and potentially blinding complication of uveitis. Many mechanisms are involved alone or in combination in the pathogenesis of uveitic glaucoma (UG). In terms of diagnostic evaluation, the effects of inflammatory activity in the retinal nerve fiber layer may be a source of bias in the interpretation of optical coherence tomography measurements. For the successful treatment of UG, the control of intraocular inflammation specific to the cause or anti-inflammatory treatment, combined with IOP management, is mandatory. The early institution of specific treatment improves the prognosis of UG associated with CMV. The young age of UG patients along with increased failure rates of glaucoma surgery in this group of patients warrants a stepwise approach. Conservative and conjunctival sparing surgical approaches should be adopted. Minimally invasive surgical approaches were proved to be effective and are increasingly being used in the management of UG along with the traditionally used techniques of trabeculectomy or tubes. This review aims to summarize the progress that recently occurred in the diagnosis and treatment of UG. |
| first_indexed | 2024-04-25T00:27:40Z |
| format | Article |
| id | doaj.art-60681148ef9f4bef921cab90b5c4793e |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-04-25T00:27:40Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-60681148ef9f4bef921cab90b5c4793e2024-03-12T16:47:30ZengMDPI AGJournal of Clinical Medicine2077-03832024-02-01135118510.3390/jcm13051185Update on Diagnosis and Treatment of Uveitic GlaucomaIoannis Halkiadakis0Kalliroi Konstantopoulou1Vasilios Tzimis2Nikolaos Papadopoulos3Klio Chatzistefanou4Nikolaos N. Markomichelakis5Ophthalmiatrion Athinon, Athens Eye Hospital, 10672 Athens, GreeceOphthalmiatrion Athinon, Athens Eye Hospital, 10672 Athens, GreeceOphthalmiatrion Athinon, Athens Eye Hospital, 10672 Athens, GreeceOphthalmiatrion Athinon, Athens Eye Hospital, 10672 Athens, GreeceFirst Department of Ophthalmology, National and Kapodistrian University of Athens School of Medicine, Athens General Hospital “G. Gennimatas”, 11527 Athenbs, GreeceOcular Inflammation Institute of Athens, Sarantaporou 7 Agios Stefanos, 14565 Athens, GreeceGlaucoma is a common and potentially blinding complication of uveitis. Many mechanisms are involved alone or in combination in the pathogenesis of uveitic glaucoma (UG). In terms of diagnostic evaluation, the effects of inflammatory activity in the retinal nerve fiber layer may be a source of bias in the interpretation of optical coherence tomography measurements. For the successful treatment of UG, the control of intraocular inflammation specific to the cause or anti-inflammatory treatment, combined with IOP management, is mandatory. The early institution of specific treatment improves the prognosis of UG associated with CMV. The young age of UG patients along with increased failure rates of glaucoma surgery in this group of patients warrants a stepwise approach. Conservative and conjunctival sparing surgical approaches should be adopted. Minimally invasive surgical approaches were proved to be effective and are increasingly being used in the management of UG along with the traditionally used techniques of trabeculectomy or tubes. This review aims to summarize the progress that recently occurred in the diagnosis and treatment of UG.https://www.mdpi.com/2077-0383/13/5/1185uveitic glaucomainflammatory glaucomaCMVminimally invasive glaucoma surgreryAhmed valveBaerveldt tube |
| spellingShingle | Ioannis Halkiadakis Kalliroi Konstantopoulou Vasilios Tzimis Nikolaos Papadopoulos Klio Chatzistefanou Nikolaos N. Markomichelakis Update on Diagnosis and Treatment of Uveitic Glaucoma Journal of Clinical Medicine uveitic glaucoma inflammatory glaucoma CMV minimally invasive glaucoma surgrery Ahmed valve Baerveldt tube |
| title | Update on Diagnosis and Treatment of Uveitic Glaucoma |
| title_full | Update on Diagnosis and Treatment of Uveitic Glaucoma |
| title_fullStr | Update on Diagnosis and Treatment of Uveitic Glaucoma |
| title_full_unstemmed | Update on Diagnosis and Treatment of Uveitic Glaucoma |
| title_short | Update on Diagnosis and Treatment of Uveitic Glaucoma |
| title_sort | update on diagnosis and treatment of uveitic glaucoma |
| topic | uveitic glaucoma inflammatory glaucoma CMV minimally invasive glaucoma surgrery Ahmed valve Baerveldt tube |
| url | https://www.mdpi.com/2077-0383/13/5/1185 |
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