Acute shock caused by Clonorchis sinensis infection: a case report
Abstract Background Clonorchiasis, caused by Clonorchis sinensis (C. sinensis) infection, is a serious food-borne zoonotic disease that is often asymptomatic or shows only mild symptoms, which leads to delayed treatment and chronic clonorchiasis and results in various complications, such as cholelit...
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| Format: | Article |
| Language: | English |
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BMC
2019-11-01
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| Series: | BMC Infectious Diseases |
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| Online Access: | https://doi.org/10.1186/s12879-019-4644-5 |
| _version_ | 1819298470050136064 |
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| author | Nan Wang Bin Tang Yuhua Hao Xue Bai Xuelin Wang Yuxiang Li Yong Yang Shicun Li Shuo Hao Xinyu Wang Mingyuan Liu Xiaolei Liu |
| author_facet | Nan Wang Bin Tang Yuhua Hao Xue Bai Xuelin Wang Yuxiang Li Yong Yang Shicun Li Shuo Hao Xinyu Wang Mingyuan Liu Xiaolei Liu |
| author_sort | Nan Wang |
| collection | DOAJ |
| description | Abstract Background Clonorchiasis, caused by Clonorchis sinensis (C. sinensis) infection, is a serious food-borne zoonotic disease that is often asymptomatic or shows only mild symptoms, which leads to delayed treatment and chronic clonorchiasis and results in various complications, such as cholelithiasis, cholangitis, cholecystitis and cholangiocarcinoma. However, acute shock caused by C. sinensis infection has not been reported. Here, for the first time, we describe a fatal case of acute shock caused by C. sinensis infection. Case presentation A patient with a history of eating raw or undercooked freshwater fish was hospitalized with acute shock caused by severe abdominal pain. Physical examination suggested acute abdomen with severe abdominal pain and rigidity. Computed tomography (CT) detection indicated acute cholecystitis and cholelithiasis. After cholecystectomy, several liver flukes were found in the drainage tube. Furthermore, morphological analysis and polymerase chain reaction (PCR) identified the pathogen as C. sinensis. The liver gradually restored normal function after anthelmintic therapy with praziquantel. Conclusions In this fatal case, C. sinensis infection was the cause of acute shock, which is rarely found in the clinic environment. This report aims to increase awareness of the hazards and complications related to clonorchiasis. The PCR diagnosis method used in this report might be helpful in reducing the misdiagnosis of clonorchiasis and unnecessary cholecystectomy. |
| first_indexed | 2024-12-24T05:30:24Z |
| format | Article |
| id | doaj.art-60687aff401f4ab6bb3ebc3cf22b03f5 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-24T05:30:24Z |
| publishDate | 2019-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-60687aff401f4ab6bb3ebc3cf22b03f52022-12-21T17:13:11ZengBMCBMC Infectious Diseases1471-23342019-11-011911510.1186/s12879-019-4644-5Acute shock caused by Clonorchis sinensis infection: a case reportNan Wang0Bin Tang1Yuhua Hao2Xue Bai3Xuelin Wang4Yuxiang Li5Yong Yang6Shicun Li7Shuo Hao8Xinyu Wang9Mingyuan Liu10Xiaolei Liu11Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis/College of Veterinary Medicine, Jilin UniversityKey Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis/College of Veterinary Medicine, Jilin UniversityAffiliated Zhongshan Hospital of Dalian UniversityKey Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis/College of Veterinary Medicine, Jilin UniversityKey Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis/College of Veterinary Medicine, Jilin UniversityInfection Department, the First Hospital of Jilin UniversityKey Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis/College of Veterinary Medicine, Jilin UniversityKey Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis/College of Veterinary Medicine, Jilin UniversityKey Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis/College of Veterinary Medicine, Jilin UniversityKey Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis/College of Veterinary Medicine, Jilin UniversityKey Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis/College of Veterinary Medicine, Jilin UniversityKey Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis/College of Veterinary Medicine, Jilin UniversityAbstract Background Clonorchiasis, caused by Clonorchis sinensis (C. sinensis) infection, is a serious food-borne zoonotic disease that is often asymptomatic or shows only mild symptoms, which leads to delayed treatment and chronic clonorchiasis and results in various complications, such as cholelithiasis, cholangitis, cholecystitis and cholangiocarcinoma. However, acute shock caused by C. sinensis infection has not been reported. Here, for the first time, we describe a fatal case of acute shock caused by C. sinensis infection. Case presentation A patient with a history of eating raw or undercooked freshwater fish was hospitalized with acute shock caused by severe abdominal pain. Physical examination suggested acute abdomen with severe abdominal pain and rigidity. Computed tomography (CT) detection indicated acute cholecystitis and cholelithiasis. After cholecystectomy, several liver flukes were found in the drainage tube. Furthermore, morphological analysis and polymerase chain reaction (PCR) identified the pathogen as C. sinensis. The liver gradually restored normal function after anthelmintic therapy with praziquantel. Conclusions In this fatal case, C. sinensis infection was the cause of acute shock, which is rarely found in the clinic environment. This report aims to increase awareness of the hazards and complications related to clonorchiasis. The PCR diagnosis method used in this report might be helpful in reducing the misdiagnosis of clonorchiasis and unnecessary cholecystectomy.https://doi.org/10.1186/s12879-019-4644-5ClonorchiasisCholecystitisAcute shockPCR |
| spellingShingle | Nan Wang Bin Tang Yuhua Hao Xue Bai Xuelin Wang Yuxiang Li Yong Yang Shicun Li Shuo Hao Xinyu Wang Mingyuan Liu Xiaolei Liu Acute shock caused by Clonorchis sinensis infection: a case report BMC Infectious Diseases Clonorchiasis Cholecystitis Acute shock PCR |
| title | Acute shock caused by Clonorchis sinensis infection: a case report |
| title_full | Acute shock caused by Clonorchis sinensis infection: a case report |
| title_fullStr | Acute shock caused by Clonorchis sinensis infection: a case report |
| title_full_unstemmed | Acute shock caused by Clonorchis sinensis infection: a case report |
| title_short | Acute shock caused by Clonorchis sinensis infection: a case report |
| title_sort | acute shock caused by clonorchis sinensis infection a case report |
| topic | Clonorchiasis Cholecystitis Acute shock PCR |
| url | https://doi.org/10.1186/s12879-019-4644-5 |
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