A case of recurrent eccrine porocarcinoma
BACKGROUND: Eccrine porocarcinoma, first described in 1963, is a rare malignant lesion arising from the eccrine sweat glands. It is usually a primary tumor, even more commonly, a malignant degeneration of an eccrine poroma. It usually affects elderly, and is located commonly in the lower extremities...
| প্রধান লেখক: | , |
|---|---|
| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
| প্রকাশিত: |
Vesnu Publications
2016-03-01
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| মালা: | Chronic Diseases Journal |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | http://cdjournal.muk.ac.ir/index.php/cdj/article/view/224 |
| _version_ | 1827956268324618240 |
|---|---|
| author | Esmaeil Sadeghi Mohamad Jafari |
| author_facet | Esmaeil Sadeghi Mohamad Jafari |
| author_sort | Esmaeil Sadeghi |
| collection | DOAJ |
| description | BACKGROUND: Eccrine porocarcinoma, first described in 1963, is a rare malignant lesion arising from the eccrine sweat glands. It is usually a primary tumor, even more commonly, a malignant degeneration of an eccrine poroma. It usually affects elderly, and is located commonly in the lower extremities. About 20% of the cases will reappear after treatment. The treatment consists of wide local excision of the primary lesion. This uncommon skin tumor is locally aggressive and has a high recurrence rate.
CASE REPORT: We report a 95-year-old woman with a large tumor on the left knee. A large number of tumoral cells showed immunolabeling of p63 supporting squamous or myoepithelial differentiation. They were also positive for cytokeratin-7 (CK7), epithelial membrane antigen (EMA), and carcinoembryonic antigen (CEA) highlight luminal differentiation in some of the vacuolated cells and this was also seen with periodic acid-Schiff-diastase (PAS-diastase) staining.
CONCLUSION: Eccrine porocarcinoma is a rare aggressive form of skin cancer with unknown etiology, and little guidance is available in the literature on exact protocols for treatment and follow up. It should be on the differential diagnosis of any suspicious skin lesion seen by the plastic surgeon. Histologic assessment is indicated in suspicious lesions.
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| first_indexed | 2024-04-09T15:01:45Z |
| format | Article |
| id | doaj.art-606990222206498fa2e579908f017567 |
| institution | Directory Open Access Journal |
| issn | 2345-2226 2588-7297 |
| language | English |
| last_indexed | 2024-04-09T15:01:45Z |
| publishDate | 2016-03-01 |
| publisher | Vesnu Publications |
| record_format | Article |
| series | Chronic Diseases Journal |
| spelling | doaj.art-606990222206498fa2e579908f0175672023-05-01T09:50:13ZengVesnu PublicationsChronic Diseases Journal2345-22262588-72972016-03-01427073https://doi.org/10.22122/cdj.v4i2.224A case of recurrent eccrine porocarcinomaEsmaeil Sadeghi0Mohamad Jafari1Student of Medicine, Student Research Committee, School of Medicine, Hamadan University of Medical Sciences, Hamadan, IranAssociate Professor, Department of Pathology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, IranBACKGROUND: Eccrine porocarcinoma, first described in 1963, is a rare malignant lesion arising from the eccrine sweat glands. It is usually a primary tumor, even more commonly, a malignant degeneration of an eccrine poroma. It usually affects elderly, and is located commonly in the lower extremities. About 20% of the cases will reappear after treatment. The treatment consists of wide local excision of the primary lesion. This uncommon skin tumor is locally aggressive and has a high recurrence rate. CASE REPORT: We report a 95-year-old woman with a large tumor on the left knee. A large number of tumoral cells showed immunolabeling of p63 supporting squamous or myoepithelial differentiation. They were also positive for cytokeratin-7 (CK7), epithelial membrane antigen (EMA), and carcinoembryonic antigen (CEA) highlight luminal differentiation in some of the vacuolated cells and this was also seen with periodic acid-Schiff-diastase (PAS-diastase) staining. CONCLUSION: Eccrine porocarcinoma is a rare aggressive form of skin cancer with unknown etiology, and little guidance is available in the literature on exact protocols for treatment and follow up. It should be on the differential diagnosis of any suspicious skin lesion seen by the plastic surgeon. Histologic assessment is indicated in suspicious lesions. http://cdjournal.muk.ac.ir/index.php/cdj/article/view/224eccrine porocarcinomarecurrencesweat glands |
| spellingShingle | Esmaeil Sadeghi Mohamad Jafari A case of recurrent eccrine porocarcinoma Chronic Diseases Journal eccrine porocarcinoma recurrence sweat glands |
| title | A case of recurrent eccrine porocarcinoma |
| title_full | A case of recurrent eccrine porocarcinoma |
| title_fullStr | A case of recurrent eccrine porocarcinoma |
| title_full_unstemmed | A case of recurrent eccrine porocarcinoma |
| title_short | A case of recurrent eccrine porocarcinoma |
| title_sort | case of recurrent eccrine porocarcinoma |
| topic | eccrine porocarcinoma recurrence sweat glands |
| url | http://cdjournal.muk.ac.ir/index.php/cdj/article/view/224 |
| work_keys_str_mv | AT esmaeilsadeghi acaseofrecurrenteccrineporocarcinoma AT mohamadjafari acaseofrecurrenteccrineporocarcinoma AT esmaeilsadeghi caseofrecurrenteccrineporocarcinoma AT mohamadjafari caseofrecurrenteccrineporocarcinoma |