Integrative Single-Cell Transcriptomic Analysis of Human Fetal Thymocyte Development

Integrative Single-Cell Transcriptomic Analysis of Human Fetal Thymocyte Development

Intrathymic differentiation of T lymphocytes begins as early as intrauterine stage, yet the T cell lineage decisions of human fetal thymocytes at different gestational ages are not currently understood. Here, we performed integrative single-cell analyses of thymocytes across gestational ages. We ide...

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Bibliographic Details
Main Authors: Yuchen Li, Weihong Zeng, Tong Li, Yanyan Guo, Guangyong Zheng, Xiaoying He, Lilian Bai, Guolian Ding, Li Jin, Xinmei Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Genetics
Subjects:
fetal thymus
human and murine
single-cell RNA-seq
T lymphopoiesis
transcriptional dynamics
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.679616/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.679616/full

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