Burden of kidney cancer and attributed risk factors in China from 1990 to 2019
BackgroundThe changing trends and risk-attributed burdens of kidney cancer in China are unknown. Therefore, this study aimed to describe the latest status and trends of kidney cancer burden in China and its associated risk factors.MethodsThe absolute numbers and rates of the incidence, deaths, and d...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-12-01
|
| Series: | Frontiers in Public Health |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2022.1062504/full |
| _version_ | 1797980581741461504 |
|---|---|
| author | Zongping Wang Zongping Wang Le Wang Song Wang Song Wang Liping Xie |
| author_facet | Zongping Wang Zongping Wang Le Wang Song Wang Song Wang Liping Xie |
| author_sort | Zongping Wang |
| collection | DOAJ |
| description | BackgroundThe changing trends and risk-attributed burdens of kidney cancer in China are unknown. Therefore, this study aimed to describe the latest status and trends of kidney cancer burden in China and its associated risk factors.MethodsThe absolute numbers and rates of the incidence, deaths, and disability-adjusted life-years (DALYs) of kidney cancer in China were extracted from the Global Burden of Disease 2019 platform. Overall burden and burden attributed to smoking and high body mass index (BMI) were described. Average annual percent change (AAPC) was calculated to describe trend analyses from 1990 to 2019 using the Joinpoint regression program.ResultsIn 2019, 59,827 new cases, 23,954 deaths, and 642,799 DALYs of kidney cancer occurred in China, of which men accounted for 71.1, 70.5, and 72.0%, and the population aged ≥55 years accounted for 58.9, 77.9, and 60.1%, of new cases, deaths, and DALYs, respectively. From 1990 to 2019, the age-standardized incidence rate (per 100,000 person-years) increased from 1.16 in 1990 to 3.21 in 2019, with an AAPC of 3.4% (95% confidence interval [CI]: 3.1–3.8%, p < 0.05); the mortality rate increased from 0.70 to 1.27, with an AAPC of 2.1% (1.5–2.3%, p < 0.05); and the DALY rate increased from 0.70 to 1.27, with an AAPC of 2.1% (1.5–2.3%, p < 0.05). In 2019, the proportions of DALYs attributed to smoking and high BMI were 18.0% and 11.1%, respectively, and the DALY rates attributed to both smoking and high BMI increased from 1990 to 2019, with AAPC of 2.9% (2.6–3.3%, p < 0.05) and 4.8% (4.2–5.4%, p < 0.05), respectively.ConclusionThe kidney cancer burden in China has continued to grow over the recent three decades, with a severe burden among older adults and men. Therefore, timely preventive interventions for modifiable risk factors are required. |
| first_indexed | 2024-04-11T05:56:21Z |
| format | Article |
| id | doaj.art-606c53af4427485b9b0f825a671d88a4 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-04-11T05:56:21Z |
| publishDate | 2022-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-606c53af4427485b9b0f825a671d88a42022-12-22T04:41:52ZengFrontiers Media S.A.Frontiers in Public Health2296-25652022-12-011010.3389/fpubh.2022.10625041062504Burden of kidney cancer and attributed risk factors in China from 1990 to 2019Zongping Wang0Zongping Wang1Le Wang2Song Wang3Song Wang4Liping Xie5The First Affiliated Hospital, Zhejiang University School of Medicine (FAHZU), Hangzhou, Zhejiang, ChinaThe Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, ChinaThe Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, ChinaThe First Affiliated Hospital, Zhejiang University School of Medicine (FAHZU), Hangzhou, Zhejiang, ChinaThe Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, ChinaThe First Affiliated Hospital, Zhejiang University School of Medicine (FAHZU), Hangzhou, Zhejiang, ChinaBackgroundThe changing trends and risk-attributed burdens of kidney cancer in China are unknown. Therefore, this study aimed to describe the latest status and trends of kidney cancer burden in China and its associated risk factors.MethodsThe absolute numbers and rates of the incidence, deaths, and disability-adjusted life-years (DALYs) of kidney cancer in China were extracted from the Global Burden of Disease 2019 platform. Overall burden and burden attributed to smoking and high body mass index (BMI) were described. Average annual percent change (AAPC) was calculated to describe trend analyses from 1990 to 2019 using the Joinpoint regression program.ResultsIn 2019, 59,827 new cases, 23,954 deaths, and 642,799 DALYs of kidney cancer occurred in China, of which men accounted for 71.1, 70.5, and 72.0%, and the population aged ≥55 years accounted for 58.9, 77.9, and 60.1%, of new cases, deaths, and DALYs, respectively. From 1990 to 2019, the age-standardized incidence rate (per 100,000 person-years) increased from 1.16 in 1990 to 3.21 in 2019, with an AAPC of 3.4% (95% confidence interval [CI]: 3.1–3.8%, p < 0.05); the mortality rate increased from 0.70 to 1.27, with an AAPC of 2.1% (1.5–2.3%, p < 0.05); and the DALY rate increased from 0.70 to 1.27, with an AAPC of 2.1% (1.5–2.3%, p < 0.05). In 2019, the proportions of DALYs attributed to smoking and high BMI were 18.0% and 11.1%, respectively, and the DALY rates attributed to both smoking and high BMI increased from 1990 to 2019, with AAPC of 2.9% (2.6–3.3%, p < 0.05) and 4.8% (4.2–5.4%, p < 0.05), respectively.ConclusionThe kidney cancer burden in China has continued to grow over the recent three decades, with a severe burden among older adults and men. Therefore, timely preventive interventions for modifiable risk factors are required.https://www.frontiersin.org/articles/10.3389/fpubh.2022.1062504/fullkidney cancerrisk factorburden of diseaseepidemiologytrends |
| spellingShingle | Zongping Wang Zongping Wang Le Wang Song Wang Song Wang Liping Xie Burden of kidney cancer and attributed risk factors in China from 1990 to 2019 Frontiers in Public Health kidney cancer risk factor burden of disease epidemiology trends |
| title | Burden of kidney cancer and attributed risk factors in China from 1990 to 2019 |
| title_full | Burden of kidney cancer and attributed risk factors in China from 1990 to 2019 |
| title_fullStr | Burden of kidney cancer and attributed risk factors in China from 1990 to 2019 |
| title_full_unstemmed | Burden of kidney cancer and attributed risk factors in China from 1990 to 2019 |
| title_short | Burden of kidney cancer and attributed risk factors in China from 1990 to 2019 |
| title_sort | burden of kidney cancer and attributed risk factors in china from 1990 to 2019 |
| topic | kidney cancer risk factor burden of disease epidemiology trends |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2022.1062504/full |
| work_keys_str_mv | AT zongpingwang burdenofkidneycancerandattributedriskfactorsinchinafrom1990to2019 AT zongpingwang burdenofkidneycancerandattributedriskfactorsinchinafrom1990to2019 AT lewang burdenofkidneycancerandattributedriskfactorsinchinafrom1990to2019 AT songwang burdenofkidneycancerandattributedriskfactorsinchinafrom1990to2019 AT songwang burdenofkidneycancerandattributedriskfactorsinchinafrom1990to2019 AT lipingxie burdenofkidneycancerandattributedriskfactorsinchinafrom1990to2019 |