Focal reactive nodular gliosis: an extremely rare retinal astrocytic tumor
Focal reactive nodular gliosis (FRNG) is an extremely rare benign retinal reactive astrocytic tumor that results from the proliferation of well-diferentiated glial cells secondary to a variety of retinal conditions. We describe a case of this tumor in a 64-year-old male in association with a chorior...
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| Format: | Article |
| Language: | English |
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German Medical Science GMS Publishing House
2023-12-01
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| Series: | GMS Ophthalmology Cases |
| Subjects: | |
| Online Access: | http://www.egms.de/static/en/journals/oc/2023-13/oc000230.shtml |
| _version_ | 1827581012645773312 |
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| author | Villoria-Díaz, Saúl Saornil-Álvarez, María Antonia García-Álvarez, Ciro García-Lagarto, Elena Bermúdez-Castellanos, Irene |
| author_facet | Villoria-Díaz, Saúl Saornil-Álvarez, María Antonia García-Álvarez, Ciro García-Lagarto, Elena Bermúdez-Castellanos, Irene |
| author_sort | Villoria-Díaz, Saúl |
| collection | DOAJ |
| description | Focal reactive nodular gliosis (FRNG) is an extremely rare benign retinal reactive astrocytic tumor that results from the proliferation of well-diferentiated glial cells secondary to a variety of retinal conditions. We describe a case of this tumor in a 64-year-old male in association with a chorioretinal scar he has had since childhood. The symptom was sudden painful vision loss. In the clinical examination, iris rubeosis, posterior synechiae, cataract, vitreous haze and a suspected fundus mass were showed. B-scan ultrasonography demonstrated a retinal mass consistent with choroidal melanoma. The magnetic resonance imaging (MRI) showed a well-circumscribed mass with T1 hyperintensity and T2 hypointensity. Enucleation was performed and histopathologic and immunohistochemical studies confirmed the diagnosis of FRNG. |
| first_indexed | 2024-03-08T22:29:21Z |
| format | Article |
| id | doaj.art-6071dab385674260b35c43a4e91d5145 |
| institution | Directory Open Access Journal |
| issn | 2193-1496 |
| language | English |
| last_indexed | 2024-03-08T22:29:21Z |
| publishDate | 2023-12-01 |
| publisher | German Medical Science GMS Publishing House |
| record_format | Article |
| series | GMS Ophthalmology Cases |
| spelling | doaj.art-6071dab385674260b35c43a4e91d51452023-12-18T06:57:56ZengGerman Medical Science GMS Publishing HouseGMS Ophthalmology Cases2193-14962023-12-0113Doc2210.3205/oc000230Focal reactive nodular gliosis: an extremely rare retinal astrocytic tumorVilloria-Díaz, Saúl0Saornil-Álvarez, María Antonia1García-Álvarez, Ciro2García-Lagarto, Elena3Bermúdez-Castellanos, Irene4University Care Complex of Palencia, Department of Ophthalmology, Palencia, SpainUniversity Clinical Hospital of Valladolid, Department of Ophthalmology, Valladolid, SpainUniversity Clinical Hospital of Valladolid, Department of Ophthalmology, Valladolid, SpainUniversity Clinical Hospital of Valladolid, Department of Pathology, Valladolid, SpainRío Hortega University Hospital, Department of Ophthalmology, Valladolid, SpainFocal reactive nodular gliosis (FRNG) is an extremely rare benign retinal reactive astrocytic tumor that results from the proliferation of well-diferentiated glial cells secondary to a variety of retinal conditions. We describe a case of this tumor in a 64-year-old male in association with a chorioretinal scar he has had since childhood. The symptom was sudden painful vision loss. In the clinical examination, iris rubeosis, posterior synechiae, cataract, vitreous haze and a suspected fundus mass were showed. B-scan ultrasonography demonstrated a retinal mass consistent with choroidal melanoma. The magnetic resonance imaging (MRI) showed a well-circumscribed mass with T1 hyperintensity and T2 hypointensity. Enucleation was performed and histopathologic and immunohistochemical studies confirmed the diagnosis of FRNG.http://www.egms.de/static/en/journals/oc/2023-13/oc000230.shtmlastrocytesglial fibrillary astrocytic proteingliosiski-67 antigenretinal neoplasm |
| spellingShingle | Villoria-Díaz, Saúl Saornil-Álvarez, María Antonia García-Álvarez, Ciro García-Lagarto, Elena Bermúdez-Castellanos, Irene Focal reactive nodular gliosis: an extremely rare retinal astrocytic tumor GMS Ophthalmology Cases astrocytes glial fibrillary astrocytic protein gliosis ki-67 antigen retinal neoplasm |
| title | Focal reactive nodular gliosis: an extremely rare retinal astrocytic tumor |
| title_full | Focal reactive nodular gliosis: an extremely rare retinal astrocytic tumor |
| title_fullStr | Focal reactive nodular gliosis: an extremely rare retinal astrocytic tumor |
| title_full_unstemmed | Focal reactive nodular gliosis: an extremely rare retinal astrocytic tumor |
| title_short | Focal reactive nodular gliosis: an extremely rare retinal astrocytic tumor |
| title_sort | focal reactive nodular gliosis an extremely rare retinal astrocytic tumor |
| topic | astrocytes glial fibrillary astrocytic protein gliosis ki-67 antigen retinal neoplasm |
| url | http://www.egms.de/static/en/journals/oc/2023-13/oc000230.shtml |
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