A capricious case of Staphylococcus caprae thoracic osteomyelitis
Staphylococcus caprae (S. caprae) is a gram positive, coagulase-negative Staphylococci (CoNS) that occurs as a commensal pathogen on the human skin. It recently has been recognized in causing nosocomial infections involving the bloodstream, urinary tract, heart, bone, and joints, particularly in imm...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | IDCases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250924000386 |
| _version_ | 1797200876872400896 |
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| author | Zoheb Irshad Sulaiman Patrick J. Tu Stephanie L. Baer Peter J. Skidmore |
| author_facet | Zoheb Irshad Sulaiman Patrick J. Tu Stephanie L. Baer Peter J. Skidmore |
| author_sort | Zoheb Irshad Sulaiman |
| collection | DOAJ |
| description | Staphylococcus caprae (S. caprae) is a gram positive, coagulase-negative Staphylococci (CoNS) that occurs as a commensal pathogen on the human skin. It recently has been recognized in causing nosocomial infections involving the bloodstream, urinary tract, heart, bone, and joints, particularly in immunosuppressed patients or individuals with prosthetic devices. Previously, S. caprae was underreported as it was difficult to identify in the clinical microbiology laboratory; however, due to advances in molecular identification methods and matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS), more clinical cases are being identified in human isolates and appropriately treated. S. caprae osteoarticular infections are usually associated with polymicrobial infections and presence of orthopedic prostheses in immunocompromised adults. This pathogen has an even rarer presentation of bone and joint infections (BJIs) in immunocompetent individuals without orthopedic devices.Our case is of a 65-year-old immunocompetent male with diet-controlled diabetes mellitus type 2 and end-stage renal disease (ESRD) on hemodialysis who presented with worsening mid-thoracic pain after a ground-level fall and was diagnosed with biopsy-proven S. caprae thoracic discitis/osteomyelitis, associated with recurrent catheter-related bloodstream infection (CRBSI). It illustrates the importance of recognizing S. caprae as an emerging human pathogen, even in immunocompetent individuals without orthopedic hardware, requiring prompt targeted treatment of native BJIs to prevent unfavorable outcomes. |
| first_indexed | 2024-04-24T07:38:37Z |
| format | Article |
| id | doaj.art-6073a4b46dd040e89d1525b700cc6c66 |
| institution | Directory Open Access Journal |
| issn | 2214-2509 |
| language | English |
| last_indexed | 2024-04-24T07:38:37Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj.art-6073a4b46dd040e89d1525b700cc6c662024-04-20T04:17:27ZengElsevierIDCases2214-25092024-01-0136e01962A capricious case of Staphylococcus caprae thoracic osteomyelitisZoheb Irshad Sulaiman0Patrick J. Tu1Stephanie L. Baer2Peter J. Skidmore3Division of Infectious Diseases, Department of Medicine, Medical College of Georgia at Wellstar MCG Health, Augusta, GA, USA; Infectious Diseases Service, VA Augusta Health Care System, Augusta, GA, USA; Corresponding author at: Division of Infectious Diseases, Department of Medicine, Medical College of Georgia at Wellstar MCG Health, Augusta, GA, USA.Department of Pharmacy, VA Augusta Health Care System, Augusta, GA, USADivision of Infectious Diseases, Department of Medicine, Medical College of Georgia at Wellstar MCG Health, Augusta, GA, USA; Infectious Diseases Service, VA Augusta Health Care System, Augusta, GA, USADivision of Infectious Diseases, Department of Medicine, Medical College of Georgia at Wellstar MCG Health, Augusta, GA, USA; Infectious Diseases Service, VA Augusta Health Care System, Augusta, GA, USAStaphylococcus caprae (S. caprae) is a gram positive, coagulase-negative Staphylococci (CoNS) that occurs as a commensal pathogen on the human skin. It recently has been recognized in causing nosocomial infections involving the bloodstream, urinary tract, heart, bone, and joints, particularly in immunosuppressed patients or individuals with prosthetic devices. Previously, S. caprae was underreported as it was difficult to identify in the clinical microbiology laboratory; however, due to advances in molecular identification methods and matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS), more clinical cases are being identified in human isolates and appropriately treated. S. caprae osteoarticular infections are usually associated with polymicrobial infections and presence of orthopedic prostheses in immunocompromised adults. This pathogen has an even rarer presentation of bone and joint infections (BJIs) in immunocompetent individuals without orthopedic devices.Our case is of a 65-year-old immunocompetent male with diet-controlled diabetes mellitus type 2 and end-stage renal disease (ESRD) on hemodialysis who presented with worsening mid-thoracic pain after a ground-level fall and was diagnosed with biopsy-proven S. caprae thoracic discitis/osteomyelitis, associated with recurrent catheter-related bloodstream infection (CRBSI). It illustrates the importance of recognizing S. caprae as an emerging human pathogen, even in immunocompetent individuals without orthopedic hardware, requiring prompt targeted treatment of native BJIs to prevent unfavorable outcomes.http://www.sciencedirect.com/science/article/pii/S2214250924000386Staphylococcus capraeS. capraeCatheter-related bloodstream infectionThoracic osteomyelitisBone and joint infectionsCoagulase-negative Staphylococci |
| spellingShingle | Zoheb Irshad Sulaiman Patrick J. Tu Stephanie L. Baer Peter J. Skidmore A capricious case of Staphylococcus caprae thoracic osteomyelitis IDCases Staphylococcus caprae S. caprae Catheter-related bloodstream infection Thoracic osteomyelitis Bone and joint infections Coagulase-negative Staphylococci |
| title | A capricious case of Staphylococcus caprae thoracic osteomyelitis |
| title_full | A capricious case of Staphylococcus caprae thoracic osteomyelitis |
| title_fullStr | A capricious case of Staphylococcus caprae thoracic osteomyelitis |
| title_full_unstemmed | A capricious case of Staphylococcus caprae thoracic osteomyelitis |
| title_short | A capricious case of Staphylococcus caprae thoracic osteomyelitis |
| title_sort | capricious case of staphylococcus caprae thoracic osteomyelitis |
| topic | Staphylococcus caprae S. caprae Catheter-related bloodstream infection Thoracic osteomyelitis Bone and joint infections Coagulase-negative Staphylococci |
| url | http://www.sciencedirect.com/science/article/pii/S2214250924000386 |
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