Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometry
LNMRI has sought to develop a methodology for the identification and accurate detection of impurities emitting gamma radiation at the metrological level, aiming to meet the recommendations not only of the international pharmacopoeia, but also of CNEN and ANVISA regarding quality control that can en...
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Format: | Article |
Language: | English |
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Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)
2017-11-01
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Series: | Brazilian Journal of Radiation Sciences |
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Online Access: | https://bjrs.org.br/revista/index.php/REVISTA/article/view/300 |
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author | Eduardo Bonfim De Paula Miriam Tainá Ferreira de Araújo Roberto Poledna José Ubiratan Delgado Anderson Leiras |
author_facet | Eduardo Bonfim De Paula Miriam Tainá Ferreira de Araújo Roberto Poledna José Ubiratan Delgado Anderson Leiras |
author_sort | Eduardo Bonfim De Paula |
collection | DOAJ |
description |
LNMRI has sought to develop a methodology for the identification and accurate detection of impurities emitting gamma radiation at the metrological level, aiming to meet the recommendations not only of the international pharmacopoeia, but also of CNEN and ANVISA regarding quality control that can ensure patients That the doses received by the practices are as low as practicable. As an initial goal, it was possible to obtain an efficiency curve with uncertainty around 1% necessary to start future measurements of interest applied to nuclear medicine and to begin the development of the impurities analysis technique.
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first_indexed | 2024-04-12T11:38:34Z |
format | Article |
id | doaj.art-6075ef52fe2f4da299616769dfa2e5cb |
institution | Directory Open Access Journal |
issn | 2319-0612 |
language | English |
last_indexed | 2024-04-12T11:38:34Z |
publishDate | 2017-11-01 |
publisher | Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR) |
record_format | Article |
series | Brazilian Journal of Radiation Sciences |
spelling | doaj.art-6075ef52fe2f4da299616769dfa2e5cb2022-12-22T03:34:44ZengBrazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)Brazilian Journal of Radiation Sciences2319-06122017-11-0153-A10.15392/bjrs.v5i3.300Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometryEduardo Bonfim De Paula0Miriam Tainá Ferreira de Araújo1Roberto Poledna2José Ubiratan Delgado3Anderson Leiras4Instituto de Rádioproteção e Dosimetria IRD/CNENPrograma de Engenharia Nuclear - PEN/COPPE/UFRJInstituto de Rádioproteção e Dosimetria IRD/CNENInstituto de Rádioproteção e Dosimetria IRD/CNENInstituto de Rádioproteção e Dosimetria IRD/CNEN LNMRI has sought to develop a methodology for the identification and accurate detection of impurities emitting gamma radiation at the metrological level, aiming to meet the recommendations not only of the international pharmacopoeia, but also of CNEN and ANVISA regarding quality control that can ensure patients That the doses received by the practices are as low as practicable. As an initial goal, it was possible to obtain an efficiency curve with uncertainty around 1% necessary to start future measurements of interest applied to nuclear medicine and to begin the development of the impurities analysis technique. https://bjrs.org.br/revista/index.php/REVISTA/article/view/300RadiopharmaceuticalsRadionuclide ImpuritiesRadionuclide Metrology. |
spellingShingle | Eduardo Bonfim De Paula Miriam Tainá Ferreira de Araújo Roberto Poledna José Ubiratan Delgado Anderson Leiras Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometry Brazilian Journal of Radiation Sciences Radiopharmaceuticals Radionuclide Impurities Radionuclide Metrology. |
title | Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometry |
title_full | Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometry |
title_fullStr | Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometry |
title_full_unstemmed | Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometry |
title_short | Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometry |
title_sort | development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma ray spectrometry |
topic | Radiopharmaceuticals Radionuclide Impurities Radionuclide Metrology. |
url | https://bjrs.org.br/revista/index.php/REVISTA/article/view/300 |
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