Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometry

LNMRI has sought to develop a methodology for the identification and accurate detection of impurities emitting gamma radiation at the metrological level, aiming to meet the recommendations not only of the international pharmacopoeia, but also of CNEN and ANVISA regarding quality control that can en...

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Main Authors: Eduardo Bonfim De Paula, Miriam Tainá Ferreira de Araújo, Roberto Poledna, José Ubiratan Delgado, Anderson Leiras
Format: Article
Language:English
Published: Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR) 2017-11-01
Series:Brazilian Journal of Radiation Sciences
Subjects:
Online Access:https://bjrs.org.br/revista/index.php/REVISTA/article/view/300
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author Eduardo Bonfim De Paula
Miriam Tainá Ferreira de Araújo
Roberto Poledna
José Ubiratan Delgado
Anderson Leiras
author_facet Eduardo Bonfim De Paula
Miriam Tainá Ferreira de Araújo
Roberto Poledna
José Ubiratan Delgado
Anderson Leiras
author_sort Eduardo Bonfim De Paula
collection DOAJ
description LNMRI has sought to develop a methodology for the identification and accurate detection of impurities emitting gamma radiation at the metrological level, aiming to meet the recommendations not only of the international pharmacopoeia, but also of CNEN and ANVISA regarding quality control that can ensure patients That the doses received by the practices are as low as practicable. As an initial goal, it was possible to obtain an efficiency curve with uncertainty around 1% necessary to start future measurements of interest applied to nuclear medicine and to begin the development of the impurities analysis technique.
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spelling doaj.art-6075ef52fe2f4da299616769dfa2e5cb2022-12-22T03:34:44ZengBrazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)Brazilian Journal of Radiation Sciences2319-06122017-11-0153-A10.15392/bjrs.v5i3.300Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometryEduardo Bonfim De Paula0Miriam Tainá Ferreira de Araújo1Roberto Poledna2José Ubiratan Delgado3Anderson Leiras4Instituto de Rádioproteção e Dosimetria IRD/CNENPrograma de Engenharia Nuclear - PEN/COPPE/UFRJInstituto de Rádioproteção e Dosimetria IRD/CNENInstituto de Rádioproteção e Dosimetria IRD/CNENInstituto de Rádioproteção e Dosimetria IRD/CNEN LNMRI has sought to develop a methodology for the identification and accurate detection of impurities emitting gamma radiation at the metrological level, aiming to meet the recommendations not only of the international pharmacopoeia, but also of CNEN and ANVISA regarding quality control that can ensure patients That the doses received by the practices are as low as practicable. As an initial goal, it was possible to obtain an efficiency curve with uncertainty around 1% necessary to start future measurements of interest applied to nuclear medicine and to begin the development of the impurities analysis technique. https://bjrs.org.br/revista/index.php/REVISTA/article/view/300RadiopharmaceuticalsRadionuclide ImpuritiesRadionuclide Metrology.
spellingShingle Eduardo Bonfim De Paula
Miriam Tainá Ferreira de Araújo
Roberto Poledna
José Ubiratan Delgado
Anderson Leiras
Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometry
Brazilian Journal of Radiation Sciences
Radiopharmaceuticals
Radionuclide Impurities
Radionuclide Metrology.
title Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometry
title_full Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometry
title_fullStr Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometry
title_full_unstemmed Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometry
title_short Development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma-ray spectrometry
title_sort development of a methodology for the analysis of radionuclide impurities in radiopharmaceuticals by gamma ray spectrometry
topic Radiopharmaceuticals
Radionuclide Impurities
Radionuclide Metrology.
url https://bjrs.org.br/revista/index.php/REVISTA/article/view/300
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