Comparison of the prognostic value of SYNTAX score and clinical SYNTAX score on outcomes of Chinese patients underwent percutaneous coronary intervention
Abstract Background Previous studies have validated the capability of SYNTAX score (SS) and clinical SYNTAX score (CSS) in the prediction of clinical outcomes in patients who have undergone PCI; however, studies on comparison of these two scoring systems in Chinese population have been sparse. Metho...
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| Format: | Article |
| Language: | English |
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BMC
2021-07-01
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| Series: | BMC Cardiovascular Disorders |
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| Online Access: | https://doi.org/10.1186/s12872-021-02144-w |
| _version_ | 1819156741497028608 |
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| author | Xiao-Qin Li Chun Yin Xiao-Li Li Wen-Li Wu Kun Cui |
| author_facet | Xiao-Qin Li Chun Yin Xiao-Li Li Wen-Li Wu Kun Cui |
| author_sort | Xiao-Qin Li |
| collection | DOAJ |
| description | Abstract Background Previous studies have validated the capability of SYNTAX score (SS) and clinical SYNTAX score (CSS) in the prediction of clinical outcomes in patients who have undergone PCI; however, studies on comparison of these two scoring systems in Chinese population have been sparse. Methods To study the ability of SS and CSS in prediction of clinical outcomes of Chinese patients underwent percutaneous coronary intervention (PCI). We retrospectively calculated SS and CSS for 547 Chinese patients from a single center who underwent PCI. Patients were stratified into tertiles according to their SS and CSS. We compared the 2-year clinical outcomes in these patients stratified separately by SS and CSS tertiles. Results The incidence of major adverse cardiac and cerebro-vascular events (MACCE) was the highest in patients with SSHIGH (13.5%), comparing to 6.8% in SSMED and 0% in SSLOW (p < 0.0001). The Cox multivariable analysis showed that the SS and CSS were both strong independent predictors for MACCE [1.100 (1.069–1.133), 1.017 (1.010–1.025), both p < 0.0001]. The receiver operating characteristic (ROC) curves showed the areas-under-the-curves for all-cause death by CSS was slightly larger comparing to SS but not significantly (AUC SS, 0.64; AUC CSS, 0.71; p = 0.23). Conclusion We concluded that both the SS and CSS were capable of risk stratification of clinical outcomes in all-comers population as well as in low and moderate risk Chinese patients undergoing PCI with CSS showing slightly better advantage. |
| first_indexed | 2024-12-22T15:57:41Z |
| format | Article |
| id | doaj.art-6079465b98b24f7f9d2f0ab338b0cf53 |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-12-22T15:57:41Z |
| publishDate | 2021-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-6079465b98b24f7f9d2f0ab338b0cf532022-12-21T18:20:45ZengBMCBMC Cardiovascular Disorders1471-22612021-07-0121111110.1186/s12872-021-02144-wComparison of the prognostic value of SYNTAX score and clinical SYNTAX score on outcomes of Chinese patients underwent percutaneous coronary interventionXiao-Qin Li0Chun Yin1Xiao-Li Li2Wen-Li Wu3Kun Cui4Department of Cardiology, Chongqing General Hospital, University of Chinese Academy of SciencesDepartment of Cardiology, Chongqing General Hospital, University of Chinese Academy of SciencesDepartment of Cardiology, Chongqing General Hospital, University of Chinese Academy of SciencesDepartment of Cardiology, Chongqing General Hospital, University of Chinese Academy of SciencesDepartment of Cardiology, Chongqing General Hospital, University of Chinese Academy of SciencesAbstract Background Previous studies have validated the capability of SYNTAX score (SS) and clinical SYNTAX score (CSS) in the prediction of clinical outcomes in patients who have undergone PCI; however, studies on comparison of these two scoring systems in Chinese population have been sparse. Methods To study the ability of SS and CSS in prediction of clinical outcomes of Chinese patients underwent percutaneous coronary intervention (PCI). We retrospectively calculated SS and CSS for 547 Chinese patients from a single center who underwent PCI. Patients were stratified into tertiles according to their SS and CSS. We compared the 2-year clinical outcomes in these patients stratified separately by SS and CSS tertiles. Results The incidence of major adverse cardiac and cerebro-vascular events (MACCE) was the highest in patients with SSHIGH (13.5%), comparing to 6.8% in SSMED and 0% in SSLOW (p < 0.0001). The Cox multivariable analysis showed that the SS and CSS were both strong independent predictors for MACCE [1.100 (1.069–1.133), 1.017 (1.010–1.025), both p < 0.0001]. The receiver operating characteristic (ROC) curves showed the areas-under-the-curves for all-cause death by CSS was slightly larger comparing to SS but not significantly (AUC SS, 0.64; AUC CSS, 0.71; p = 0.23). Conclusion We concluded that both the SS and CSS were capable of risk stratification of clinical outcomes in all-comers population as well as in low and moderate risk Chinese patients undergoing PCI with CSS showing slightly better advantage.https://doi.org/10.1186/s12872-021-02144-wSYNTAX scoreClinical SYNTAX scorePercutaneous coronary interventionClinical outcomes |
| spellingShingle | Xiao-Qin Li Chun Yin Xiao-Li Li Wen-Li Wu Kun Cui Comparison of the prognostic value of SYNTAX score and clinical SYNTAX score on outcomes of Chinese patients underwent percutaneous coronary intervention BMC Cardiovascular Disorders SYNTAX score Clinical SYNTAX score Percutaneous coronary intervention Clinical outcomes |
| title | Comparison of the prognostic value of SYNTAX score and clinical SYNTAX score on outcomes of Chinese patients underwent percutaneous coronary intervention |
| title_full | Comparison of the prognostic value of SYNTAX score and clinical SYNTAX score on outcomes of Chinese patients underwent percutaneous coronary intervention |
| title_fullStr | Comparison of the prognostic value of SYNTAX score and clinical SYNTAX score on outcomes of Chinese patients underwent percutaneous coronary intervention |
| title_full_unstemmed | Comparison of the prognostic value of SYNTAX score and clinical SYNTAX score on outcomes of Chinese patients underwent percutaneous coronary intervention |
| title_short | Comparison of the prognostic value of SYNTAX score and clinical SYNTAX score on outcomes of Chinese patients underwent percutaneous coronary intervention |
| title_sort | comparison of the prognostic value of syntax score and clinical syntax score on outcomes of chinese patients underwent percutaneous coronary intervention |
| topic | SYNTAX score Clinical SYNTAX score Percutaneous coronary intervention Clinical outcomes |
| url | https://doi.org/10.1186/s12872-021-02144-w |
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