Neuromuscular transmission studies in human chronic Chagas' disease
An electrophysiological investigation of the state of the neuromuscular transmission (nmt) was carried out in 58 patients with the diagnosis of chronic Chagas' disease. On repetitive supramaximal nerve stimulation it was found that some patients did not show abnormalities, others had decrementa...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Neurologia (ABNEURO)
1989-09-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1989000300004&lng=en&tlng=en |
| _version_ | 1818874072075862016 |
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| author | Marcela Garcia Erro O. Genovese J. Correale R. E. P. Sica |
| author_facet | Marcela Garcia Erro O. Genovese J. Correale R. E. P. Sica |
| author_sort | Marcela Garcia Erro |
| collection | DOAJ |
| description | An electrophysiological investigation of the state of the neuromuscular transmission (nmt) was carried out in 58 patients with the diagnosis of chronic Chagas' disease. On repetitive supramaximal nerve stimulation it was found that some patients did not show abnormalities, others had decremental muscle responses, others developed enhancement of the muscle evoked potential amplitudes, while some other patients combined both types of pathological responses. The findings suggest that some patients with chronic Chagas' disease develop impairement of nmt, though data obtained in this study do not give information about neither the type of impairement nor the localization (pre or postsynaptic, or both) of the damage. |
| first_indexed | 2024-12-19T13:04:47Z |
| format | Article |
| id | doaj.art-607aa785c5b346488c1ec01a27f89f18 |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-19T13:04:47Z |
| publishDate | 1989-09-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-607aa785c5b346488c1ec01a27f89f182022-12-21T20:20:05ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42271989-09-0147327928210.1590/S0004-282X1989000300004S0004-282X1989000300004Neuromuscular transmission studies in human chronic Chagas' diseaseMarcela Garcia Erro0O. Genovese1J. Correale2R. E. P. Sica3Hospital General de Agudos J. M. Ramos MejíaHospital General de Agudos J. M. Ramos MejíaHospital General de Agudos J. M. Ramos MejíaHospital General de Agudos J. M. Ramos MejíaAn electrophysiological investigation of the state of the neuromuscular transmission (nmt) was carried out in 58 patients with the diagnosis of chronic Chagas' disease. On repetitive supramaximal nerve stimulation it was found that some patients did not show abnormalities, others had decremental muscle responses, others developed enhancement of the muscle evoked potential amplitudes, while some other patients combined both types of pathological responses. The findings suggest that some patients with chronic Chagas' disease develop impairement of nmt, though data obtained in this study do not give information about neither the type of impairement nor the localization (pre or postsynaptic, or both) of the damage.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1989000300004&lng=en&tlng=en |
| spellingShingle | Marcela Garcia Erro O. Genovese J. Correale R. E. P. Sica Neuromuscular transmission studies in human chronic Chagas' disease Arquivos de Neuro-Psiquiatria |
| title | Neuromuscular transmission studies in human chronic Chagas' disease |
| title_full | Neuromuscular transmission studies in human chronic Chagas' disease |
| title_fullStr | Neuromuscular transmission studies in human chronic Chagas' disease |
| title_full_unstemmed | Neuromuscular transmission studies in human chronic Chagas' disease |
| title_short | Neuromuscular transmission studies in human chronic Chagas' disease |
| title_sort | neuromuscular transmission studies in human chronic chagas disease |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1989000300004&lng=en&tlng=en |
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