Ribosome biogenesis in disease: new players and therapeutic targets

Ribosome biogenesis in disease: new players and therapeutic targets

Abstract The ribosome is a multi-unit complex that translates mRNA into protein. Ribosome biogenesis is the process that generates ribosomes and plays an essential role in cell proliferation, differentiation, apoptosis, development, and transformation. The mTORC1, Myc, and noncoding RNA signaling pa...

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Bibliographic Details
Main Authors: Lijuan Jiao, Yuzhe Liu, Xi-Yong Yu, Xiangbin Pan, Yu Zhang, Junchu Tu, Yao-Hua Song, Yangxin Li
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-022-01285-4

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