Read-SpaM: assembly-free and alignment-free comparison of bacterial genomes with low sequencing coverage
Abstract Background In many fields of biomedical research, it is important to estimate phylogenetic distances between taxa based on low-coverage sequencing reads. Major applications are, for example, phylogeny reconstruction, species identification from small sequencing samples, or bacterial strain...
Main Authors: | Anna-Katharina Lau, Svenja Dörrer, Chris-André Leimeister, Christoph Bleidorn, Burkhard Morgenstern |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-019-3205-7 |
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