Current Developments on Optical Feedback Interferometry as an All-Optical Sensor for Biomedical Applications
Optical feedback interferometry (OFI) sensors are experiencing a consistent increase in their applications to biosensing due to their contactless nature, low cost and compactness, features that fit very well with current biophotonics research and market trends. The present paper is a review of the w...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2016-05-01
|
| Series: | Sensors |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1424-8220/16/5/694 |
| _version_ | 1798026706324291584 |
|---|---|
| author | Julien Perchoux Adam Quotb Reza Atashkhooei Francisco J. Azcona Evelio E. Ramírez-Miquet Olivier Bernal Ajit Jha Antonio Luna-Arriaga Carlos Yanez Jesus Caum Thierry Bosch Santiago Royo |
| author_facet | Julien Perchoux Adam Quotb Reza Atashkhooei Francisco J. Azcona Evelio E. Ramírez-Miquet Olivier Bernal Ajit Jha Antonio Luna-Arriaga Carlos Yanez Jesus Caum Thierry Bosch Santiago Royo |
| author_sort | Julien Perchoux |
| collection | DOAJ |
| description | Optical feedback interferometry (OFI) sensors are experiencing a consistent increase in their applications to biosensing due to their contactless nature, low cost and compactness, features that fit very well with current biophotonics research and market trends. The present paper is a review of the work in progress at UPC-CD6 and LAAS-CNRS related to the application of OFI to different aspects of biosensing, both in vivo and ex vivo. This work is intended to present the variety of opportunities and potential applications related to OFI that are available in the field. The activities presented are divided into two main sensing strategies: The measurement of optical path changes and the monitoring of flows, which correspond to sensing strategies linked to the reconstruction of changes of amplitude from the interferometric signal, and to classical Doppler frequency measurements, respectively. For optical path change measurements, measurements of transient pulses, usual in biosensing, together with the measurement of large displacements applied to designing palliative care instrumentation for Parkinson disease are discussed. Regarding the Doppler-based approach, progress in flow-related signal processing and applications in real-time monitoring of non-steady flows, human blood flow monitoring and OFI pressure myograph sensing will be presented. In all cases, experimental setups are discussed and results presented, showing the versatility of the technique. The described applications show the wide capabilities in biosensing of the OFI sensor, showing it as an enabler of low-cost, all-optical, high accuracy biomedical applications. |
| first_indexed | 2024-04-11T18:39:44Z |
| format | Article |
| id | doaj.art-6080724c9da141dd840a978048f8cb8b |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-11T18:39:44Z |
| publishDate | 2016-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-6080724c9da141dd840a978048f8cb8b2022-12-22T04:09:02ZengMDPI AGSensors1424-82202016-05-0116569410.3390/s16050694s16050694Current Developments on Optical Feedback Interferometry as an All-Optical Sensor for Biomedical ApplicationsJulien Perchoux0Adam Quotb1Reza Atashkhooei2Francisco J. Azcona3Evelio E. Ramírez-Miquet4Olivier Bernal5Ajit Jha6Antonio Luna-Arriaga7Carlos Yanez8Jesus Caum9Thierry Bosch10Santiago Royo11LAAS-CNRS, Université de Toulouse, CNRS, INP, 6 AllÃée Emile Monso, 31400 Toulouse, FranceLAAS-CNRS, Université de Toulouse, CNRS, INP, 6 AllÃée Emile Monso, 31400 Toulouse, FranceCentre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, SpainCentre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, SpainLAAS-CNRS, Université de Toulouse, CNRS, INP, 6 AllÃée Emile Monso, 31400 Toulouse, FranceLAAS-CNRS, Université de Toulouse, CNRS, INP, 6 AllÃée Emile Monso, 31400 Toulouse, FranceCentre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, SpainLAAS-CNRS, Université de Toulouse, CNRS, INP, 6 AllÃée Emile Monso, 31400 Toulouse, FranceCentre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, SpainCentre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, SpainLAAS-CNRS, Université de Toulouse, CNRS, INP, 6 AllÃée Emile Monso, 31400 Toulouse, FranceCentre for the Development of Sensors, Instruments and Systems, Universitat Politècnica de Catalunya (UPC-CD6), Rambla Sant Nebridi 10, E08222 Terrassa, SpainOptical feedback interferometry (OFI) sensors are experiencing a consistent increase in their applications to biosensing due to their contactless nature, low cost and compactness, features that fit very well with current biophotonics research and market trends. The present paper is a review of the work in progress at UPC-CD6 and LAAS-CNRS related to the application of OFI to different aspects of biosensing, both in vivo and ex vivo. This work is intended to present the variety of opportunities and potential applications related to OFI that are available in the field. The activities presented are divided into two main sensing strategies: The measurement of optical path changes and the monitoring of flows, which correspond to sensing strategies linked to the reconstruction of changes of amplitude from the interferometric signal, and to classical Doppler frequency measurements, respectively. For optical path change measurements, measurements of transient pulses, usual in biosensing, together with the measurement of large displacements applied to designing palliative care instrumentation for Parkinson disease are discussed. Regarding the Doppler-based approach, progress in flow-related signal processing and applications in real-time monitoring of non-steady flows, human blood flow monitoring and OFI pressure myograph sensing will be presented. In all cases, experimental setups are discussed and results presented, showing the versatility of the technique. The described applications show the wide capabilities in biosensing of the OFI sensor, showing it as an enabler of low-cost, all-optical, high accuracy biomedical applications.http://www.mdpi.com/1424-8220/16/5/694optical feedback interferometrybiosensorsvibrometryflowmetrybiophotonicsmetrology |
| spellingShingle | Julien Perchoux Adam Quotb Reza Atashkhooei Francisco J. Azcona Evelio E. Ramírez-Miquet Olivier Bernal Ajit Jha Antonio Luna-Arriaga Carlos Yanez Jesus Caum Thierry Bosch Santiago Royo Current Developments on Optical Feedback Interferometry as an All-Optical Sensor for Biomedical Applications Sensors optical feedback interferometry biosensors vibrometry flowmetry biophotonics metrology |
| title | Current Developments on Optical Feedback Interferometry as an All-Optical Sensor for Biomedical Applications |
| title_full | Current Developments on Optical Feedback Interferometry as an All-Optical Sensor for Biomedical Applications |
| title_fullStr | Current Developments on Optical Feedback Interferometry as an All-Optical Sensor for Biomedical Applications |
| title_full_unstemmed | Current Developments on Optical Feedback Interferometry as an All-Optical Sensor for Biomedical Applications |
| title_short | Current Developments on Optical Feedback Interferometry as an All-Optical Sensor for Biomedical Applications |
| title_sort | current developments on optical feedback interferometry as an all optical sensor for biomedical applications |
| topic | optical feedback interferometry biosensors vibrometry flowmetry biophotonics metrology |
| url | http://www.mdpi.com/1424-8220/16/5/694 |
| work_keys_str_mv | AT julienperchoux currentdevelopmentsonopticalfeedbackinterferometryasanallopticalsensorforbiomedicalapplications AT adamquotb currentdevelopmentsonopticalfeedbackinterferometryasanallopticalsensorforbiomedicalapplications AT rezaatashkhooei currentdevelopmentsonopticalfeedbackinterferometryasanallopticalsensorforbiomedicalapplications AT franciscojazcona currentdevelopmentsonopticalfeedbackinterferometryasanallopticalsensorforbiomedicalapplications AT evelioeramirezmiquet currentdevelopmentsonopticalfeedbackinterferometryasanallopticalsensorforbiomedicalapplications AT olivierbernal currentdevelopmentsonopticalfeedbackinterferometryasanallopticalsensorforbiomedicalapplications AT ajitjha currentdevelopmentsonopticalfeedbackinterferometryasanallopticalsensorforbiomedicalapplications AT antoniolunaarriaga currentdevelopmentsonopticalfeedbackinterferometryasanallopticalsensorforbiomedicalapplications AT carlosyanez currentdevelopmentsonopticalfeedbackinterferometryasanallopticalsensorforbiomedicalapplications AT jesuscaum currentdevelopmentsonopticalfeedbackinterferometryasanallopticalsensorforbiomedicalapplications AT thierrybosch currentdevelopmentsonopticalfeedbackinterferometryasanallopticalsensorforbiomedicalapplications AT santiagoroyo currentdevelopmentsonopticalfeedbackinterferometryasanallopticalsensorforbiomedicalapplications |