QSAR study for anti-HIV-1 activities of HEPT derivatives using MLR and PLS
A QSAR study using Multiple Linear Regression (MLR) and a Partial Least Squares (PLS) methodology was performed for a series of 127 derivatives of 1-(2-hydroxy-ethoxy)methyl]-6-(phenylthio)-timine (HEPT), a potent inhibitor of the of the human immunodeficiency virus type 1, HIV-1 reverse transcr...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Serbian Chemical Society
2013-01-01
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Series: | Journal of the Serbian Chemical Society |
Subjects: | |
Online Access: | http://www.doiserbia.nb.rs/img/doi/0352-5139/2013/0352-51391200085I.pdf |