QSAR study for anti-HIV-1 activities of HEPT derivatives using MLR and PLS

A QSAR study using Multiple Linear Regression (MLR) and a Partial Least Squares (PLS) methodology was performed for a series of 127 derivatives of 1-(2-hydroxy-ethoxy)methyl]-6-(phenylthio)-timine (HEPT), a potent inhibitor of the of the human immunodeficiency virus type 1, HIV-1 reverse transcr...

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Bibliographic Details
Main Authors: Ivan Daniela, Crisan Luminita, Funar-Timofei Simona, Mracec Mircea
Format: Article
Language:English
Published: Serbian Chemical Society 2013-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2013/0352-51391200085I.pdf