Protective Effect of Resveratrol on Benzo(a)Pyrene Induced Dysfunctions of Steroidogenesis and Steroidogenic Acute Regulatory Gene Expression in Leydig Cells

Protective Effect of Resveratrol on Benzo(a)Pyrene Induced Dysfunctions of Steroidogenesis and Steroidogenic Acute Regulatory Gene Expression in Leydig Cells

Benzo(a)pyrene [B(a)P] is the toxic environmental Polycyclic Aromatic Hydrocarbon (PAH), that exerts male reproductive dysfunctions. In this study the molecular mechanism of B(a)P induced Leydig cell steroidogenic dysfunctions and its protective mechanism of action with a natural Aryl hydrocarbon re...

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Bibliographic Details
Main Authors: Bhaswati Banerjee, Supriya Chakraborty, Pratip Chakraborty, Debidas Ghosh, Kuladip Jana
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Endocrinology
Subjects:
B(a)P
leydig cell
ROS
StAR
p38 MAPK
SF1
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00272/full

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