Genomic Hippo Pathway Alterations and Persistent YAP/TAZ Activation: New Hallmarks in Head and Neck Cancer

Genomic Hippo Pathway Alterations and Persistent YAP/TAZ Activation: New Hallmarks in Head and Neck Cancer

Head and neck squamous cell carcinoma (HNSCC) represents a highly prevalent and deadly malignancy worldwide. The prognosis for locoregionally advanced HNSCC has not appreciably improved over the past 30 years despite advances in surgical, radiation, and targeted therapies and less than 20% of HNSCC...

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Bibliographic Details
Main Authors: Farhoud Faraji, Sydney I. Ramirez, Paola Y. Anguiano Quiroz, Amaya N. Mendez-Molina, J. Silvio Gutkind
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
head and neck squamous cell carcinoma
HNSC
HNSCC
Hippo
YAP
TAZ
Online Access:https://www.mdpi.com/2073-4409/11/8/1370

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