Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft Recipient
The immunosuppressive state in organ transplantation leads to infectious complications responsible for high mortality rate. Fungal infections account for 5% of all infections in Renal Transplantation (RT) recipients. Aspergillus species are filamentous fungi frequently causing fungal infections in...
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Format: | Article |
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JCDR Research and Publications Private Limited
2017-07-01
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Series: | Journal of Clinical and Diagnostic Research |
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Online Access: | https://jcdr.net/articles/PDF/10288/27919_CE[Ra]_F(Sh)_PF1(PG_SS)_PFA(P_PG).pdf |
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author | Minaxi H Patel Aruna V Vanikar Himanshu V Patel Rashmi D Patel |
author_facet | Minaxi H Patel Aruna V Vanikar Himanshu V Patel Rashmi D Patel |
author_sort | Minaxi H Patel |
collection | DOAJ |
description | The immunosuppressive state in organ transplantation leads to infectious complications responsible for high mortality rate.
Fungal infections account for 5% of all infections in Renal Transplantation (RT) recipients. Aspergillus species are filamentous
fungi frequently causing fungal infections in RT recipients. Lungs and paranasal sinuses are the usual portal of entry from where
it disseminates to other organs. Here, we are reporting a case of 14-year-old boy with RT from mother’s kidney, who had atypical
presentation of isolated cerebral aspergillosis at 19 months post-transplant without identified portal of entry. Early diagnosis and
prompt treatment saved the patient and the graft. |
first_indexed | 2024-12-19T02:25:17Z |
format | Article |
id | doaj.art-608d2a6a8a38452caf03591ecffcc48a |
institution | Directory Open Access Journal |
issn | 2249-782X 0973-709X |
language | English |
last_indexed | 2024-12-19T02:25:17Z |
publishDate | 2017-07-01 |
publisher | JCDR Research and Publications Private Limited |
record_format | Article |
series | Journal of Clinical and Diagnostic Research |
spelling | doaj.art-608d2a6a8a38452caf03591ecffcc48a2022-12-21T20:39:58ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-07-01117DD01DD0210.7860/JCDR/2017/27919.10288Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft RecipientMinaxi H Patel0Aruna V Vanikar1Himanshu V Patel2Rashmi D Patel3Assistant Professor, Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases and Research Centre (IKDRC) - Dr. H.L. Trivedi, Ahmedabad, Gujarat, India.Professor and Head, Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases and Research Centre (IKDRC) - Dr. H.L. Trivedi, Ahmedabad, Gujarat, India.Professor, Department of Nephrology and Transplantation Medicine, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases and Research Centre (IKDRC) - Dr. H.L. Trivedi, Ahmedabad, Gujarat, India.Professor, Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi, Ahmedabad, Gujarat, India.The immunosuppressive state in organ transplantation leads to infectious complications responsible for high mortality rate. Fungal infections account for 5% of all infections in Renal Transplantation (RT) recipients. Aspergillus species are filamentous fungi frequently causing fungal infections in RT recipients. Lungs and paranasal sinuses are the usual portal of entry from where it disseminates to other organs. Here, we are reporting a case of 14-year-old boy with RT from mother’s kidney, who had atypical presentation of isolated cerebral aspergillosis at 19 months post-transplant without identified portal of entry. Early diagnosis and prompt treatment saved the patient and the graft.https://jcdr.net/articles/PDF/10288/27919_CE[Ra]_F(Sh)_PF1(PG_SS)_PFA(P_PG).pdfaspergillusimmunosuppressionkidney transplantation |
spellingShingle | Minaxi H Patel Aruna V Vanikar Himanshu V Patel Rashmi D Patel Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft Recipient Journal of Clinical and Diagnostic Research aspergillus immunosuppression kidney transplantation |
title | Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft Recipient |
title_full | Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft Recipient |
title_fullStr | Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft Recipient |
title_full_unstemmed | Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft Recipient |
title_short | Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft Recipient |
title_sort | atypical presentation of isolated cerebral aspergillosis in a renal allograft recipient |
topic | aspergillus immunosuppression kidney transplantation |
url | https://jcdr.net/articles/PDF/10288/27919_CE[Ra]_F(Sh)_PF1(PG_SS)_PFA(P_PG).pdf |
work_keys_str_mv | AT minaxihpatel atypicalpresentationofisolatedcerebralaspergillosisinarenalallograftrecipient AT arunavvanikar atypicalpresentationofisolatedcerebralaspergillosisinarenalallograftrecipient AT himanshuvpatel atypicalpresentationofisolatedcerebralaspergillosisinarenalallograftrecipient AT rashmidpatel atypicalpresentationofisolatedcerebralaspergillosisinarenalallograftrecipient |