Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft Recipient

The immunosuppressive state in organ transplantation leads to infectious complications responsible for high mortality rate. Fungal infections account for 5% of all infections in Renal Transplantation (RT) recipients. Aspergillus species are filamentous fungi frequently causing fungal infections in...

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Main Authors: Minaxi H Patel, Aruna V Vanikar, Himanshu V Patel, Rashmi D Patel
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2017-07-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/10288/27919_CE[Ra]_F(Sh)_PF1(PG_SS)_PFA(P_PG).pdf
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author Minaxi H Patel
Aruna V Vanikar
Himanshu V Patel
Rashmi D Patel
author_facet Minaxi H Patel
Aruna V Vanikar
Himanshu V Patel
Rashmi D Patel
author_sort Minaxi H Patel
collection DOAJ
description The immunosuppressive state in organ transplantation leads to infectious complications responsible for high mortality rate. Fungal infections account for 5% of all infections in Renal Transplantation (RT) recipients. Aspergillus species are filamentous fungi frequently causing fungal infections in RT recipients. Lungs and paranasal sinuses are the usual portal of entry from where it disseminates to other organs. Here, we are reporting a case of 14-year-old boy with RT from mother’s kidney, who had atypical presentation of isolated cerebral aspergillosis at 19 months post-transplant without identified portal of entry. Early diagnosis and prompt treatment saved the patient and the graft.
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spelling doaj.art-608d2a6a8a38452caf03591ecffcc48a2022-12-21T20:39:58ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-07-01117DD01DD0210.7860/JCDR/2017/27919.10288Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft RecipientMinaxi H Patel0Aruna V Vanikar1Himanshu V Patel2Rashmi D Patel3Assistant Professor, Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases and Research Centre (IKDRC) - Dr. H.L. Trivedi, Ahmedabad, Gujarat, India.Professor and Head, Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases and Research Centre (IKDRC) - Dr. H.L. Trivedi, Ahmedabad, Gujarat, India.Professor, Department of Nephrology and Transplantation Medicine, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases and Research Centre (IKDRC) - Dr. H.L. Trivedi, Ahmedabad, Gujarat, India.Professor, Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi, Ahmedabad, Gujarat, India.The immunosuppressive state in organ transplantation leads to infectious complications responsible for high mortality rate. Fungal infections account for 5% of all infections in Renal Transplantation (RT) recipients. Aspergillus species are filamentous fungi frequently causing fungal infections in RT recipients. Lungs and paranasal sinuses are the usual portal of entry from where it disseminates to other organs. Here, we are reporting a case of 14-year-old boy with RT from mother’s kidney, who had atypical presentation of isolated cerebral aspergillosis at 19 months post-transplant without identified portal of entry. Early diagnosis and prompt treatment saved the patient and the graft.https://jcdr.net/articles/PDF/10288/27919_CE[Ra]_F(Sh)_PF1(PG_SS)_PFA(P_PG).pdfaspergillusimmunosuppressionkidney transplantation
spellingShingle Minaxi H Patel
Aruna V Vanikar
Himanshu V Patel
Rashmi D Patel
Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft Recipient
Journal of Clinical and Diagnostic Research
aspergillus
immunosuppression
kidney transplantation
title Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft Recipient
title_full Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft Recipient
title_fullStr Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft Recipient
title_full_unstemmed Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft Recipient
title_short Atypical Presentation of Isolated Cerebral Aspergillosis in a Renal Allograft Recipient
title_sort atypical presentation of isolated cerebral aspergillosis in a renal allograft recipient
topic aspergillus
immunosuppression
kidney transplantation
url https://jcdr.net/articles/PDF/10288/27919_CE[Ra]_F(Sh)_PF1(PG_SS)_PFA(P_PG).pdf
work_keys_str_mv AT minaxihpatel atypicalpresentationofisolatedcerebralaspergillosisinarenalallograftrecipient
AT arunavvanikar atypicalpresentationofisolatedcerebralaspergillosisinarenalallograftrecipient
AT himanshuvpatel atypicalpresentationofisolatedcerebralaspergillosisinarenalallograftrecipient
AT rashmidpatel atypicalpresentationofisolatedcerebralaspergillosisinarenalallograftrecipient