Infant acute myocarditis mimicking acute myocardial infarction

Myocarditis is an inflammatory disease of the myocardium with heterogeneous clinical manifestations and progression. In clinical practice, although there are many methods of diagnosis of acute myocarditis, the diagnosis remains an embarrassing dilemma for clinicians. The authors report the case of 9...

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Main Authors: Maher Jedidi, Samia Tilouche, Tasnim Masmoudi, Maha Sahnoun, Youssef Chkirbène, Sarra Mestiri, Lamia Boughamoura, Mohamed Ben Dhiab, Mohamed Kamel Souguir
Format: Article
Language:English
Published: University of São Paulo 2016-12-01
Series:Autopsy and Case Reports
Subjects:
Online Access:http://www.revistas.usp.br/autopsy/article/view/125431
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author Maher Jedidi
Samia Tilouche
Tasnim Masmoudi
Maha Sahnoun
Youssef Chkirbène
Sarra Mestiri
Lamia Boughamoura
Mohamed Ben Dhiab
Mohamed Kamel Souguir
author_facet Maher Jedidi
Samia Tilouche
Tasnim Masmoudi
Maha Sahnoun
Youssef Chkirbène
Sarra Mestiri
Lamia Boughamoura
Mohamed Ben Dhiab
Mohamed Kamel Souguir
author_sort Maher Jedidi
collection DOAJ
description Myocarditis is an inflammatory disease of the myocardium with heterogeneous clinical manifestations and progression. In clinical practice, although there are many methods of diagnosis of acute myocarditis, the diagnosis remains an embarrassing dilemma for clinicians. The authors report the case of 9-month-old infant who was brought to the Pediatric Emergency Department with sudden onset dyspnea. Examination disclosed heart failure and resuscitation was undertaken. The electrocardiogram showed an ST segment elevation in the anterolateral leads with a mirror image. Cardiac enzyme tests revealed a significant elevation of troponin and creatine phosphokinase levels. A diagnosis of acute myocardial infarction was made, and heparin therapy was prescribed. The infant died on the third day after admission with cardiogenic shock. The autopsy showed dilatation of the ventricles and massive edema of the lungs. Histological examinations of myocardium samples revealed the presence of a marked lymphocytic infiltrate dissociating myocardiocytes. Death was attributed to acute myocarditis. The authors call attention to the difficulties of differential diagnosis between acute myocarditis and acute myocardial infarction especially in children, and to the important therapeutic implications of a correct diagnosis
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spelling doaj.art-608d9fecf6354b2c8665bafa1120969a2022-12-21T17:58:30ZengUniversity of São PauloAutopsy and Case Reports2236-19602016-12-016410.4322/acr.2016.052Infant acute myocarditis mimicking acute myocardial infarctionMaher Jedidi0Samia Tilouche1Tasnim Masmoudi2Maha Sahnoun3Youssef Chkirbène4Sarra Mestiri5Lamia Boughamoura6Mohamed Ben Dhiab7Mohamed Kamel Souguir8Farhat Hached University Hospital. Department of Legal MedicineFarhat Hached University Hospital. Department of PediatricsFarhat Hached University Hospital. Department of Legal MedicineFarhat Hached University Hospital. Department of Legal MedicineFarhat Hached University Hospital. Department of Legal MedicineFarhat Hached University Hospital. Department of PathologyFarhat Hached University Hospital. Department of PediatricsFarhat Hached University Hospital. Department of Legal MedicineFarhat Hached University Hospital. Department of Legal MedicineMyocarditis is an inflammatory disease of the myocardium with heterogeneous clinical manifestations and progression. In clinical practice, although there are many methods of diagnosis of acute myocarditis, the diagnosis remains an embarrassing dilemma for clinicians. The authors report the case of 9-month-old infant who was brought to the Pediatric Emergency Department with sudden onset dyspnea. Examination disclosed heart failure and resuscitation was undertaken. The electrocardiogram showed an ST segment elevation in the anterolateral leads with a mirror image. Cardiac enzyme tests revealed a significant elevation of troponin and creatine phosphokinase levels. A diagnosis of acute myocardial infarction was made, and heparin therapy was prescribed. The infant died on the third day after admission with cardiogenic shock. The autopsy showed dilatation of the ventricles and massive edema of the lungs. Histological examinations of myocardium samples revealed the presence of a marked lymphocytic infiltrate dissociating myocardiocytes. Death was attributed to acute myocarditis. The authors call attention to the difficulties of differential diagnosis between acute myocarditis and acute myocardial infarction especially in children, and to the important therapeutic implications of a correct diagnosishttp://www.revistas.usp.br/autopsy/article/view/125431MyocarditisMyocardial InfarctionDiagnosisDifferentialInfant Death
spellingShingle Maher Jedidi
Samia Tilouche
Tasnim Masmoudi
Maha Sahnoun
Youssef Chkirbène
Sarra Mestiri
Lamia Boughamoura
Mohamed Ben Dhiab
Mohamed Kamel Souguir
Infant acute myocarditis mimicking acute myocardial infarction
Autopsy and Case Reports
Myocarditis
Myocardial Infarction
Diagnosis
Differential
Infant Death
title Infant acute myocarditis mimicking acute myocardial infarction
title_full Infant acute myocarditis mimicking acute myocardial infarction
title_fullStr Infant acute myocarditis mimicking acute myocardial infarction
title_full_unstemmed Infant acute myocarditis mimicking acute myocardial infarction
title_short Infant acute myocarditis mimicking acute myocardial infarction
title_sort infant acute myocarditis mimicking acute myocardial infarction
topic Myocarditis
Myocardial Infarction
Diagnosis
Differential
Infant Death
url http://www.revistas.usp.br/autopsy/article/view/125431
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AT sarramestiri infantacutemyocarditismimickingacutemyocardialinfarction
AT lamiaboughamoura infantacutemyocarditismimickingacutemyocardialinfarction
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