Photoimmunotherapy Using Cationic and Anionic Photosensitizer-Antibody Conjugates against HIV Env-Expressing Cells

Photoimmunotherapy Using Cationic and Anionic Photosensitizer-Antibody Conjugates against HIV Env-Expressing Cells

Different therapeutic strategies have been investigated to target and eliminate HIV-1-infected cells by using armed antibodies specific to viral proteins, with varying degrees of success. Herein, we propose a new strategy by combining photodynamic therapy (PDT) with HIV Env-targeted immunotherapy, a...

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Bibliographic Details
Main Authors: Mohammad Sadraeian, Calise Bahou, Edgar Ferreira da Cruz, Luíz Mário Ramos Janini, Ricardo Sobhie Diaz, Ross W. Boyle, Vijay Chudasama, Francisco Eduardo Gontijo Guimarães
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
HIV immunotherapy
photoimmunotherapy
photodynamic therapy
porphyrin
phthalocyanine
HIV-infected cell
Online Access:https://www.mdpi.com/1422-0067/21/23/9151

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