Two Phosphoglucomutase Paralogs Facilitate Ionophore-Triggered Secretion of the <italic toggle="yes">Toxoplasma</italic> Micronemes

Two Phosphoglucomutase Paralogs Facilitate Ionophore-Triggered Secretion of the <italic toggle="yes">Toxoplasma</italic> Micronemes

ABSTRACT Paralogs of the widely prevalent phosphoglucomutase (PGM) protein called parafusin function in calcium (Ca2+)-mediated exocytosis across eukaryotes. In Toxoplasma gondii, the parafusin-related protein 1 (PRP1) has been associated with Ca2+-dependent microneme organelle secretion required fo...

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Bibliographic Details
Main Authors: Sudeshna Saha, Bradley I. Coleman, Rashmi Dubey, Ira J. Blader, Marc-Jan Gubbels
Format: Article
Language:English
Published: American Society for Microbiology 2017-12-01
Series:mSphere
Subjects:
PRP1
Toxoplasma gondii
calcium
micronemes
parafusin
phosphoglucomutase
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00521-17

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