Association between autoimmune diseases and mental disorders in children and adolescents

Introduction Autoimmune diseases play a role in the etiology of a range of psychotic disorders which has attracted increasing interest in recent decades. This hypothesis is supported by genetic findings linking markers related to the immune system and mental disorders, and by clinical studies revea...

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Main Authors: Z. Elmaataoui, H. Belhadga, H. Kisra
Format: Article
Language:English
Published: Cambridge University Press 2023-03-01
Series:European Psychiatry
Online Access:https://www.cambridge.org/core/product/identifier/S0924933823015766/type/journal_article
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author Z. Elmaataoui
H. Belhadga
H. Kisra
author_facet Z. Elmaataoui
H. Belhadga
H. Kisra
author_sort Z. Elmaataoui
collection DOAJ
description Introduction Autoimmune diseases play a role in the etiology of a range of psychotic disorders which has attracted increasing interest in recent decades. This hypothesis is supported by genetic findings linking markers related to the immune system and mental disorders, and by clinical studies revealing increased levels of inflammatory markers in patients with mental disorders Objectives The objective of our work is to discuss the involvement of autoimmune diseases in the development of mental disorders in children and adolescents. Methods We conducted our study through the analysis of three clinical observations. Results These were three patients followed in the child psychiatry department for a characterized depressive disorder, an ASD and an acute psychotic attack, and in whom an autoimmune disease was revealed either in the history or on paraclinical explorations. Conclusions It appears legitimate to evoke and search for these autoimmune pathologies among the other organic etiologies, in front of any child or adolescent presenting acute and atypical psychiatric symptoms, tables of cognitive regression and resistances to the usual treatments. Biological immunological examinations, even invasive ones, should be repeated, if necessary. Disclosure of Interest None Declared
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spelling doaj.art-609495a056154e128e24e482fdd074402023-11-17T05:08:23ZengCambridge University PressEuropean Psychiatry0924-93381778-35852023-03-0166S749S74910.1192/j.eurpsy.2023.1576Association between autoimmune diseases and mental disorders in children and adolescentsZ. Elmaataoui0H. Belhadga1H. Kisra2Hospital AR-Razi of Sale, Sale, MoroccoHospital AR-Razi of Sale, Sale, MoroccoHospital AR-Razi of Sale, Sale, Morocco Introduction Autoimmune diseases play a role in the etiology of a range of psychotic disorders which has attracted increasing interest in recent decades. This hypothesis is supported by genetic findings linking markers related to the immune system and mental disorders, and by clinical studies revealing increased levels of inflammatory markers in patients with mental disorders Objectives The objective of our work is to discuss the involvement of autoimmune diseases in the development of mental disorders in children and adolescents. Methods We conducted our study through the analysis of three clinical observations. Results These were three patients followed in the child psychiatry department for a characterized depressive disorder, an ASD and an acute psychotic attack, and in whom an autoimmune disease was revealed either in the history or on paraclinical explorations. Conclusions It appears legitimate to evoke and search for these autoimmune pathologies among the other organic etiologies, in front of any child or adolescent presenting acute and atypical psychiatric symptoms, tables of cognitive regression and resistances to the usual treatments. Biological immunological examinations, even invasive ones, should be repeated, if necessary. Disclosure of Interest None Declaredhttps://www.cambridge.org/core/product/identifier/S0924933823015766/type/journal_article
spellingShingle Z. Elmaataoui
H. Belhadga
H. Kisra
Association between autoimmune diseases and mental disorders in children and adolescents
European Psychiatry
title Association between autoimmune diseases and mental disorders in children and adolescents
title_full Association between autoimmune diseases and mental disorders in children and adolescents
title_fullStr Association between autoimmune diseases and mental disorders in children and adolescents
title_full_unstemmed Association between autoimmune diseases and mental disorders in children and adolescents
title_short Association between autoimmune diseases and mental disorders in children and adolescents
title_sort association between autoimmune diseases and mental disorders in children and adolescents
url https://www.cambridge.org/core/product/identifier/S0924933823015766/type/journal_article
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