Rapamycin Induces Autophagy and Reduces the Apoptosis of Podocytes Under a Stimulated Condition of Immunoglobulin A Nephropathy

Rapamycin Induces Autophagy and Reduces the Apoptosis of Podocytes Under a Stimulated Condition of Immunoglobulin A Nephropathy

Backgroud/Aims: The aim of this study was to investigate the potential renoprotective effect of rapamycin on the autophagy of podocytes treated with the supernatant of mesangial cells cultured with aggregated IgA1 (aIgA1) from immunoglobulin A nephropathy (IgAN) patients. Methods: Monomeric IgA1 (mI...

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Bibliographic Details
Main Authors: Shikai Liang, Juan Jin, Bo Lin, Jianguang Gong, Yiwen Li, Qiang He
Format: Article
Language:English
Published: Karger Publishers 2017-04-01
Series:Kidney & Blood Pressure Research
Subjects:
Immunoglobulin A nephropathy
Light chain 3
Rapamycin
Autophagy
Podocyte
Online Access:http://www.karger.com/Article/FullText/475484

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